Impaired cellular immunity to SARS-CoV-2 in severe COVID-19 patients

L Ni, ML Cheng, Y Feng, H Zhao, J Liu, F Ye… - Frontiers in …, 2021 - frontiersin.org
The high infection rate and rapid spread of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) make it a world-wide pandemic. Individuals infected by the virus exhibited …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Immune-inflammatory parameters in COVID-19 cases: a systematic review and meta-analysis

X Feng, S Li, Q Sun, J Zhu, B Chen, M Xiong… - Frontiers in …, 2020 - frontiersin.org
Background: The recent outbreak of coronavirus disease 2019 (COVID-19) has been rapidly
spreading on a global scale and poses a great threat to human health. Acute respiratory …

[HTML][HTML] Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2

R Gasser, M Cloutier, J Prévost, C Fink, É Ducas… - Cell reports, 2021 - cell.com
Characterization of the humoral response to SARS-CoV-2, the etiological agent of COVID-
19, is essential to help control the infection. The neutralization activity of plasma from …

Humoral immune mechanisms involved in protective and pathological immunity during COVID-19

G Widjaja, AT Jalil, HS Rahman, WK Abdelbasset… - Human Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is
associated with excessive inflammation, as a main reason for severe condition and death …

Association between inflammatory cytokines and anti-SARS-CoV-2 antibodies in hospitalized patients with COVID-19

X Jing, M Xu, D Song, T Yue, Y Wang, P Zhang… - Immunity & …, 2022 - Springer
Background COVID-19 patients may experience “cytokine storm” when human immune
system produces excessive cytokines/chemokines. However, it remains unclear whether …

Clinical and autoimmune characteristics of severe and critical cases of COVID‐19

Y Zhou, T Han, J Chen, C Hou, L Hua… - Clinical and …, 2020 - Wiley Online Library
In this study we report on the clinical and autoimmune characteristics of severe and critical
novel coronavirus pneumonia caused by severe acute respiratory syndrome‒associated …

Dysregulation of the immune response affects the outcome of critical COVID‐19 patients

L Wei, W Wang, D Chen, B Xu - Journal of Medical Virology, 2020 - Wiley Online Library
Critical cases of coronavirus disease 2019 (COVID‐19) are associated with a high risk of
mortality. It remains unclear why patients with the same critical condition have different …

Unique immunological profile in patients with COVID-19

S Varchetta, D Mele, B Oliviero, S Mantovani… - Cellular & molecular …, 2021 - nature.com
The relationship between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
and host immunity is poorly understood. We performed an extensive analysis of immune …

[HTML][HTML] Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19

L Zhang, R Pang, X Xue, J Bao, S Ye, Y Dai… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Background: Anti-SARS-CoV-2 virus antibody levels in convalescent plasma (CP), which
may be useful in severe Anti-SARS-CoV-2 virus infections, have been rarely reported …