Purpose: The aim of this study was to identify morphological differences between active and
non-active areas of outflow in normal human eyes and to further identify additional structural …

Purpose: This study aimed to determine outflow patterns and morphological changes
responsible for decreased outflow facility (C) in eyes with primary open angle glaucoma …

Purpose: To compare the morphological changes in the distal outflow pathway between
primary open angle glaucoma (POAG) and age-matched normal eyes, with an emphasis on …

Purpose: Previous studies in human eyes suggest that outflow through the trabecular
meshwork (TM) and inner wall (IW) of Schlemm's canal is segmental. Whether these …

Primary open-angle glaucoma (POAG) is an age-related disease and a multifaceted optic
neuropathy characterized by the loss of optic nerve axons and retinal ganglion cells …

Purpose:: We previously reported that elevation of intraocular pressure (IOP) leads to a
progressive collapse of the aqueous plexus near the collector channel ostia in non-human …

Previous tracer studies have shown segmental outflow in the trabecular meshwork (TM) and
along the inner wall (IW) of Schlemm's canal (SC). Whether segmental outflow is conserved …

Background Elevation of intraocular pressure is usually associated with primary open angle
glaucoma and caused by increased outflow resistance. A two-color fluorescent tracer …

This review summarizes the goals and outcomes of the eighth annual ARVO/Pfizer
Ophthalmic Research Institute conference that was held on May 4th and 5th, 2012, at the …

Purpose: To investigate the flow pattern in unconventional outflow and its correlation with
conventional outflow in mouse eyes. Methods: Fluorescent microspheres were injected into …