Voltage-sensitive fluorescent proteins (VSFPs) are a family of genetically-encoded voltage
indicators (GEVIs) reporting membrane voltage fluctuation from genetically-targeted cells in …

Understanding how behavior emerges from brain electrical activity is one of the ultimate
goals of neuroscience. To achieve this goal we require methods for large‐scale recording of …

Cortical information processing relies on synaptic interactions between diverse classes of
neurons with distinct electrophysiological and connection properties. Uncovering the …

The combination of optical imaging methods with targeted expression of protein-based
fluorescent probes constitutes a powerful approach for functional analysis of selected cell …

Traditional small molecule voltage sensitive dye indicators have been a powerful tool for
monitoring large scale dynamics of neuronal activities but have several limitations including …

Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling
the function of neuronal circuits but is challenging due to the limited performance of existing …

Genetically encoded voltage indicators (GEVIs) promise to reveal the membrane potential of
genetically targeted neuronal populations through noninvasive, chronic imaging of large …

Voltage imaging of many neurons simultaneously at single-cell resolution is hampered by
the difficulty of detecting small voltage signals from overlapping neuronal processes in …

Imaging voltage using fluorescent-based sensors could be an ideal technique to probe
neural circuits with high spatiotemporal resolution. However, due to insufficient signal-to …

Deciphering how the brain generates cognitive function from patterns of electrical signals is
one of the ultimate challenges in neuroscience. To this end, it would be highly desirable to …