Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects …
KN Borrelli, KK Wingfield, EJ Yao, CA Zamorano… - …, 2023 - Elsevier
Prenatal opioid exposure is a major health concern in the United States, with the incidence
of neonatal opioid withdrawal syndrome (NOWS) escalating in recent years. NOWS occurs …
of neonatal opioid withdrawal syndrome (NOWS) escalating in recent years. NOWS occurs …
Sex differences in behavioral and brainstem transcriptomic neuroadaptations following neonatal opioid exposure in outbred mice
The opioid epidemic led to an increase in the number of neonatal opioid withdrawal
syndrome (NOWS) cases in infants born to opioid-dependent mothers. Hallmark features of …
syndrome (NOWS) cases in infants born to opioid-dependent mothers. Hallmark features of …
[HTML][HTML] Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice
AD Dunn, SA Robinson, C Nwokafor, M Estill… - Frontiers in Behavioral …, 2023 - frontiersin.org
Introduction Infants exposed to opioids in utero are at high risk of exhibiting Neonatal Opioid
Withdrawal Syndrome (NOWS), a combination of somatic withdrawal symptoms including …
Withdrawal Syndrome (NOWS), a combination of somatic withdrawal symptoms including …
Neonatal Opioid Withdrawal Syndrome in Mice: Acute Molecular and Long‐Term Behavioral Consequences
JR Ferrante, AD Dunn, J Mengaziol… - The FASEB …, 2022 - Wiley Online Library
Populations affected by the ongoing opioid epidemic include pregnant women and their
offspring. Infants exposed to opioids in utero are at risk of developing Neonatal Opioid …
offspring. Infants exposed to opioids in utero are at risk of developing Neonatal Opioid …
Differences in withdrawal symptoms, microglia activity, and cognitive functioning in rats exposed to continuous low-dose heroin in-utero
SL Mills-Huffnagle, CN Zawatsky, G Bryant… - Neurotoxicology and …, 2024 - Elsevier
Introduction Opioid use during pregnancy and subsequent neonatal opioid withdrawal
syndrome (NOWS) have been associated with poor developmental outcomes including …
syndrome (NOWS) have been associated with poor developmental outcomes including …
[HTML][HTML] Opioid withdrawal behavior in spiny mice: A novel preclinical model of neonatal opioid withdrawal syndrome (NOWS)
S Stevens, S Mohan - Heliyon, 2021 - cell.com
As the opioid epidemic continues to grow, opioid use among pregnant women is increasing
significantly. This has led to a steady rise in the number of infants born with neonatal opioid …
significantly. This has led to a steady rise in the number of infants born with neonatal opioid …
Perinatal oxycodone exposure causes long-term sex-dependent changes in weight trajectory and sensory processing in adult mice
Rationale In utero opioid exposure is associated with lower weight and a neonatal opioid
withdrawal syndrome (NOWS) at birth, along with longer-term adverse neurodevelopmental …
withdrawal syndrome (NOWS) at birth, along with longer-term adverse neurodevelopmental …
[HTML][HTML] Perigestational Opioid Exposure Alters Alcohol-Driven Reward Behaviors in Adolescent Rats
CT Searles, HJ Harder, ME Vogt, AZ Murphy - bioRxiv, 2023 - ncbi.nlm.nih.gov
Every fifteen minutes, a baby is born in the US experiencing neonatal opioid withdrawal
syndrome (NOWS). Since 2004, the rate of NOWS has increased 7-fold. Clinical studies …
syndrome (NOWS). Since 2004, the rate of NOWS has increased 7-fold. Clinical studies …
Developmental opioid exposures: neurobiological underpinnings, behavioral impacts, and policy implications
SS Goldfarb, GD Stanwood, HA Flynn… - Experimental …, 2020 - journals.sagepub.com
The devastating impact of opioid abuse and dependence on the individual, family, and
society are well known but extremely difficult to combat. During pregnancy, opioid drugs and …
society are well known but extremely difficult to combat. During pregnancy, opioid drugs and …
[HTML][HTML] Advances in animal models of prenatal opioid exposure
JR Ferrante, JA Blendy - Trends in Neurosciences, 2024 - cell.com
Neonatal opioid withdrawal syndrome (NOWS) is a growing public health concern. The
complexity of in utero opioid exposure in clinical studies makes it difficult to investigate …
complexity of in utero opioid exposure in clinical studies makes it difficult to investigate …