Mesenchymal stem cells (MSCs) are a promising regenerative medicine. The roles of
miRNAs in osteogenic differentiation of bone marrow MSCs (BM-MSCs) remained less …

Abstract Forkhead box O1 (FOXO1) is a key regulator of osteogenesis. The aim of this study
was to identify the mechanisms of microRNAs (miRNAs) targeting FOXO1 in osteogenic …

In this study, we aimed to investigate the expression of miR-145 before and after hASCs
osteogenic differentiation. We also intended to explore the influence of the target …

This study examined the hypothesis that the microRNA miR-138-5p reduces the
osteodifferentiation of human bone mesenchymal stem cells (hBMSCs) by downregulating …

Background The available therapeutic options for large bone defects remain extremely
limited, requiring new strategies to accelerate bone healing. Genetically modified bone …

Osteosarcoma (OS), occurring in mesenchymal tissues and with a high degree of
malignancy, is most common in children and adolescents. At present, we intend to figure out …

Recently, microRNAs (miRNAs) have been identified as key regulators of the proliferation
and differentiation of mesenchymal stem cells (MSCs). Our previous in vivo study and other …

Emerging evidence proves that exosomes contain specific microRNAs (miRNAs) contribute
to osteogenic differentiation of bone marrow stem cells (BMSCs). However, the role and …

Uncontrolled oxidative stress impairs bone formation and induces age‐related bone loss in
humans. The FoxO family is widely accepted to play an important role in protecting diverse …

Background Bone marrow mesenchymal stem cells (BMSCs) exhibit the capacity to self-
renew and differentiate into multi-lineage cell types, including osteoblasts, which are crucial …