Liver cells, like most other eukaryotic cell types, display numerous membrane proteins,
including receptor molecules, at their cell surface. Among their many features, specific …

Transport of macromolecules into the cell by receptor-mediated endocytosis follows a
complex series of intracellular transfers, passing through distinct environments. The …

The asialoglycoprotein receptor is a calcium-dependent, carbohydrate-specific, type C
lectin, which is majorly present in the plasma membrane of liver cells (hepatocytes). The …

The nature of the relationships between the structure and expression of the
asialoglycoprotein receptor (ASGP-R) are now becoming evident. The proposed receptor …

The asialoglycoprotein receptor (ASGP-R) of mammalian liver is a lectin that recognizes
terminal galactose and N-acetylgalactosamine (GalNAc). Elegant and pioneering studies …

Asialoglycoprotein receptors, responsible for the removal of circulating asialogly‐coproteins
by the liver, are located in at least two different membrane locations in hepatocytes …

The asialoglycoprotein receptor (ASGPr) on hepatocytes plays a role in the clearance of
desialylated proteins from the serum. Although its sugar preference (N-acetylgalactosamine …

The hepatic asialoglycoprotein receptor, a non-covalent hetero-oligomer of two subunits, is
a constitutively cycling endocytic receptor. However, the ligand asialoorosomucoid caused …

The hepatocyte asialoglycoprotein receptor is able to mediate the internalization of ligand in
buffer devoid of Na+ but containing 0.15 M K+. Under these conditions, degradation of …

The asialoglycoprotein receptor is an abundant hetero-oligomeric endocytic receptor that is
predominantly expressed on the sinusoidal surface of the hepatocytes. A number of …