The gut microbiome modulates colon tumorigenesis
Recent studies have shown that individuals with colorectal cancer have an altered gut
microbiome compared to healthy controls. It remains unclear whether these differences are …
microbiome compared to healthy controls. It remains unclear whether these differences are …
Manipulation of the gut microbiota reveals role in colon tumorigenesis
There is growing evidence that individuals with colonic adenomas and carcinomas harbor a
distinct microbiota. Alterations to the gut microbiota may allow the outgrowth of bacterial …
distinct microbiota. Alterations to the gut microbiota may allow the outgrowth of bacterial …
[HTML][HTML] Structure of the gut microbiome following colonization with human feces determines colonic tumor burden
Background A growing body of evidence indicates that the gut microbiome plays a role in
the development of colorectal cancer (CRC). Patients with CRC harbor gut microbiomes that …
the development of colorectal cancer (CRC). Patients with CRC harbor gut microbiomes that …
[HTML][HTML] Microbiome in colorectal cancer: how to get from meta-omics to mechanism?
D Ternes, J Karta, M Tsenkova, P Wilmes, S Haan… - Trends in …, 2020 - cell.com
Mounting evidence from metagenomic analyses suggests that a state of pathological
microbial imbalance or dysbiosis is prevalent in the gut of patients with colorectal cancer …
microbial imbalance or dysbiosis is prevalent in the gut of patients with colorectal cancer …
[HTML][HTML] Analysis of the intestinal lumen microbiota in an animal model of colorectal cancer
Q Zhu, Z Jin, W Wu, R Gao, B Guo, Z Gao, Y Yang… - PloS one, 2014 - journals.plos.org
Recent reports have suggested that multiple factors such as host genetics, environment and
diet can promote the progression of healthy mucosa towards sporadic colorectal carcinoma …
diet can promote the progression of healthy mucosa towards sporadic colorectal carcinoma …
[HTML][HTML] The intestinal microbiota in colorectal cancer
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …
[HTML][HTML] Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential
E Saus, S Iraola-Guzmán, JR Willis… - Molecular aspects of …, 2019 - Elsevier
The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …
years, there has been a surge of interest in assessing the relationships between the gut …
[HTML][HTML] Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer
X Liang, H Li, G Tian, S Li - Scientific reports, 2014 - nature.com
Bacterial colonisation of the gut is involved in the development of colitis-associated
colorectal cancer. However, it remains unclear how the gut microbiota dynamically shifts …
colorectal cancer. However, it remains unclear how the gut microbiota dynamically shifts …
Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer
W Zhu, N Miyata, MG Winter, A Arenales… - Journal of experimental …, 2019 - rupress.org
Chronic inflammation and gut microbiota dysbiosis, in particular the bloom of genotoxin-
producing E. coli strains, are risk factors for the development of colorectal cancer. Here, we …
producing E. coli strains, are risk factors for the development of colorectal cancer. Here, we …
[HTML][HTML] Gut microbiota modulate CD8 T cell responses to influence colitis-associated tumorigenesis
IY Amy, L Zhao, KA Eaton, S Ho, J Chen, S Poe… - Cell reports, 2020 - cell.com
There is increasing evidence that gut microbiome perturbations, also known as dysbiosis,
can influence colorectal cancer development. To understand the mechanisms by which the …
can influence colorectal cancer development. To understand the mechanisms by which the …