Molecular mechanisms that lead to reduced expression of Duffy antigens

K Yazdanbakhsh, M Rios, JR Storry, N Kosower… - …, 2000 - Wiley Online Library
BACKGROUND: In the Duffy blood group system, the null phenotype Fy (a–b–) has been
classically associated with a mutated GATA box, while the Fyx phenotype weak Fyb is …

[HTML][HTML] Molecular basis of the Duffy blood group system

G Höher, M Fiegenbaum, S Almeida - Blood Transfusion, 2018 - ncbi.nlm.nih.gov
ACKR1, located on chromosome 1q23. 2, is the gene that encodes a glycoprotein
expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants …

Duffy blood group phenotype–genotype correlations using high‐resolution melting analysis PCR and microarray reveal complex cases including a new null FY*A …

GH Lopez, J Morrison, JA Condon, B Wilson… - Vox …, 2015 - Wiley Online Library
Background and objectives Duffy blood group phenotypes can be predicted by genotyping
for single nucleotide polymorphisms (SNP s) responsible for the Fya/Fyb polymorphism, for …

Characterization of the Duffy gene promotor: evidence for tissue-specific abolishment of expression in Fy (a− b−) of black individuals

S Iwamoto, J Li, N Sugimoto, H Okuda, E Kajii - … and biophysical research …, 1996 - Elsevier
We have previously identified a novel first exon of Duffy gene and two inverse GATA motifs
in the 600 bp 5′ flanking region. The proximal GATA is positioned downstream from the …

[PDF][PDF] Fy^ x is associated with two missense point mutations in its gene and can be detected by PCR-SSP

C Gassner, RL Kraus, T Dovc… - …, 2000 - scholar.archive.org
FY* B polymorphism is caused by a missense point mutation at NT 129 of the Duffy gene,
changing Gly42 in Fya to Asp42 in Fyb. 18–20, 22 In Fy (a–b–) people, most of whom are …

[PDF][PDF] The Duffy blood group system: a review

GM Meny - Immunohematology, 2010 - researchgate.net
Duffy was the first blood group mapped to an autosome (chromosome 1) using cytogenetic
studies. Duffy antigens are located on a glycoprotein that can be found on erythrocytes and …

DNA analysis of Duffy genes in American blacks

JM Moulds, S Hayes, TD Wells - Vox sanguinis, 1998 - karger.com
Background: Because limited studies have shown that the Duffy genotype is not accurately
reflected by the erythrocyte phenotype, we used PCR-RFLP to determine the true FY1 and …

[HTML][HTML] Duffy blood group genotyping in Thai blood donors

O Nathalang, K Intharanut… - Annals of …, 2015 - synapse.koreamed.org
Background Duffy (FY) blood group genotyping is important in transfusion medicine
because Duffy alloantibodies are associated with delayed hemolytic transfusion reactions …

A clinically applicable method for determining the three major alleles at the Duffy (FY) blood group locus using polymerase chain reaction with allele‐specific primers

ML Olsson, C Hansson, ND Avent, IE Akesson… - …, 1998 - Wiley Online Library
BACKGROUND: The clinically significant antigens of the Duffy (Fy [FY]) blood group system
are expressed on the red cell form of the FY glycoprotein, a promiscuous chemokine …

Present status of the Duffy blood group system: articles reviewed

WL Marsh, PJ Schmidt - CRC critical reviews in clinical laboratory …, 1975 - Taylor & Francis
The Duffy blood group has five antigenic specificities, Fya, Fyb, Fy3, Fy4, and Fy5, that are
part of, or related to, the system. The first four antigens are under the genetic control of a …