Alkaloids of Adhatoda vasica Nees. as potential inhibitors of cyclooxygenases – an in-silico study

P Ghanta, M Doble, B Ramaiah - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Eicosanoid pathways play a crucial role in the progression and resolution of inflammation.
NSAIDs act as anti-inflammatory agents by inhibiting both the isoforms of cyclooxygenases …

[PDF][PDF] In Silico Studies On Tithonia Diversifolia Derived Phytochemicals As Potent Inhibitor Of Cyclooxygenase

OC Ejelonu, OO Elekofehinti, IO Omotuyi… - Mintage Journal of …, 2016 - researchgate.net
Objectives: Prostaglandins released by the activity of the bifunctional enzyme,
cyclooxygenase (COX) are involved in physiological functions such as protection of the …

In silico anti-inflammatory activity evaluation from usnea misaminensis through molecular docking approach

R Al-Ghani, WP Nirwani, TN Novianti… - Chemistry and …, 2022 - piscience.org
Usnea misaminensis is an epiphytic medicinal plant from Indonesia that has several
benefits, one of which is as an anti-inflammatory. This study aims to predict the ability of …

Potential of pyrroquinazoline alkaloids from Adhatoda vasica Nees. as inhibitors of 5-LOX – a computational and an in-vitro study

P Ghanta, S Sinha, M Doble… - Journal of Biomolecular …, 2022 - Taylor & Francis
Inflammation plays a major role in the onset and progression of many diseases related to the
respiratory system. Cysteinyl leukotrienes, the products of 5-LOX are a potent …

An Insilico evaluation of phytocompounds from Albizia amara and Phyla nodiflora as cyclooxygenase-2 enzyme inhibitors

Y Loganathan, M Jain, S Thiyagarajan… - DARU Journal of …, 2021 - Springer
Abstract Purpose The enzyme Cyclooxygenases (COX-1 and COX-2) catalyze the formation
of prostaglandin, a mediator of the inflammatory pathway. Inflammation related pathological …

Potential Adenostemma lavenia and Muntingia calabura extracts to inhibit cyclooxygenase-2 activity as a therapeutic strategy for anti-inflammation: experimental and …

B Tuwalaid, D Iswantini… - Indonesian Journal of …, 2022 - journal.ugm.ac.id
Continuous inflammation can cause new and more severe diseases, thus effective
treatments are needed. One of the common inflammation treatments is given by reducing …

Molecular docking study and molecular dynamic simulation of human cyclooxygenase-2 (COX-2) with selected eutypoids

L Taidi, A Maurady, MR Britel - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Inflammation is a key factor linked to almost all chronic and degenerative diseases implicit
with certain levels of pain. In studies, over the past few years, it has been discovered that …

Bridging the Chemical Profile and Biomedical Effects of Scutellaria edelbergii Essential Oils

M Shah, S Bibi, Z Kamal, JN Al-Sabahi, T Alam, O Ullah… - Antioxidants, 2022 - mdpi.com
The present study explored chemical constituents of Scutellaria edelbergii essential oils
(SEEO) for the first time, extracted through hydro-distillation, and screened them against the …

Evaluation of Selective COX-2 Inhibition and In Silico Study of Kuwanon Derivatives Isolated from Morus alba

SH Baek, S Hwang, T Park, YJ Kwon, M Cho… - International Journal of …, 2021 - mdpi.com
Six kuwanon derivatives (A/B/C/E/H/J) extracted from the roots of Morus alba L. were
evaluated to determine their cyclooxygenase (COX)-1 and 2 inhibitory effects …

In-silico anti-inflammatory potential of guaiane dimers from Xylopia vielana targeting COX-2

SS Hassan, WD Zhang, H Jin, SH Basha… - Journal of …, 2022 - Taylor & Francis
Natural products of herbal origin are prodigious to display diverse pharmacological
activities. In the present study, five guaiane-type sesquiterpene dimers, xylopidimers A− E (1 …