Molecular docking studies of Rhizophora mucronata alkaloids against neuro-inflammatory marker cyclooxygenase 2.

V Manigandan, S Gurudeeban, K Satyavani… - 2014 - cabidigitallibrary.org
Computer aided drug design is playing an important role in identifying the drug targets. The
contribution of cyclooxygenase-2 (COX-2) to peripheral inflammation and brain inflammation …

Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5-LOX by molecular docking and dynamic …

KN Hemavathi, S Skariyachan, R Raju… - Computers in Biology …, 2024 - Elsevier
Inflammation plays a pivotal role in various pathological processes, ranging from routine
injuries and infections to cancer. Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) …

Pharmacophore model, docking, QSAR, and molecular dynamics simulation studies of substituted cyclic imides and herbal medicines as COX-2 inhibitors

N Moussa, A Hassan, S Gharaghani - Heliyon, 2021 - cell.com
Abstract Cyclooxygenase-2 (COX-2) enzyme inhibitors have not eliminated the necessity for
developed drugs not only in the nonsteroidal anti-inflammatory drug (NSAIDs) area, but also …

Virtual screening and invitro evaluation of cyclooxygenase inhibitors from Tinospora cordifolia using the machine learning tool

A Mathe, V Mulpuru, SK Katari… - Journal of …, 2023 - Taylor & Francis
Tinospora cordifolia has a variety of compounds, and some of these compounds may have
anti-inflammatory and antioxidant properties. In the present study, we identified the …

Medicinal and toxicological investigation of some common NSAIDs; A computer-aided drug design approach

M Uzzaman, K Fatema, S Akhter, MR Hossain… - Journal of Molecular …, 2023 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for the treatment of pain,
fever, and inflammation. Their consumption rises some crucial side effects like …

[PDF][PDF] Structure-based in silico study of 6-gingerol, 6-ghogaol, and 6-paradol, active compounds of ginger (Zingiber officinale) as COX-2 inhibitors

NM Saptarini, EY Sitorus, J Levita - International Journal of Chemistry, 2013 - Citeseer
Ginger's (Zingiber officinale) phenolic compounds, that are 6-gingerol, 6-shogaol, and 6-
paradol, have been proven to show anti-inflammatory activity. The purpose of this paper was …

Molecular docking study of anti-inflammatory biomarkers in sulawesi propolis as potent inhibitors of cyclooxygenase-2

D Flamandita, M Sahlan, K Lischer… - 2019 IEEE …, 2019 - ieeexplore.ieee.org
NSAIDs seemingly arrived in their usage limitations as inflammatory drugs due to showing
several side effects including gastrointestinal ulcerogenic activity and kidney dysfunction …

[PDF][PDF] Potential usage of Zerumbone to suppress inflammation: An in silico study

M Amanat, AFMSU Daula, F Islam - 2021 - academia.edu
ABSTRACT A significant cyclic sesquiterpenoid known as Zerumbone was extracted from
Zingiber roseum using the volume liquid chromatographic (VLC) technique. It'sa naturally …

Fimbristylis aestivalis Vahl: a potential source of cyclooxygenase-2 (COX-2) inhibitors

S Talukder, KS Ahmed, H Hossain, T Hasan… - …, 2022 - Springer
Abstract Cyclooxygenase-2 (COX-2) is an inducible enzyme that accelerates the
biosynthesis of PGs during inflammation and has emerged as an important therapeutic …

Bioactive phytoconstituents of ethanolic extract from Chromolaena odorata leaves interact with vascular endothelial growth factor and cyclooxygenase-2: A molecular …

TRT Husni, D Darmawi, A Azwar… - Journal of Advanced …, 2023 - journals.lww.com
Chromolaenaodorata is an invasive plant with a broad spectrum of medicinal properties,
including wound healing. This study aimed to evaluate the interaction of the already …