[引用][C] Acute promyelocytic leukemia with i(17)(q10) on G‐banding and PML/RARA rearrangement by RT‐PCR without evidence of PML/RARA rearrangement on …

J Huh, H Moon, H Chi, W Chung - International Journal of …, 2009 - Wiley Online Library
The cytogenetic hallmark of acute promyelocytic leukemia (APL) is t (15; 17)(q22; q21)
involving the PML gene on chromosome 15q22 and the RARA gene on chromosome …

Derivative (7) t (7; 8): The sole karyotype abnormality in acute promyelocytic leukemia with PML/RARA rearrangement identified by RT-PCR and sequence analysis

Y Wang, M Fang, Y Jing, J Li, F Jiang, Y Wang - Leukemia research, 2009 - Elsevier
We reported a case with acute promyelocytic leukemia (APL) without t (15; 17)
translocations by conventional cytogenetics, interphase fluorescence in situ hybridisation …

Identification of PML–RARA rearrangement by RT-PCR and sequencing in an acute promyelocytic leukemia without t (15; 17) on G-banding and FISH

JY Han, KE Kim, KH Kim, JI Park, JS Kim - Leukemia research, 2007 - Elsevier
Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation, t (15;
17)(q22; q12), resulting in fusion of the genes promyelocytic leukemia (PML) and retinoic …

Novel PML-RARA fusion gene on chromosome 17 in acute promyelocytic leukemia with normal chromosome 15 and 17

KH Kim, JH Won, KJ Jeung, SC Lee… - The Korean Journal …, 2007 - synapse.koreamed.org
We describe a patient with acute promyelocytic leukemia (APL) with no detectable
cytogenetic abnormality of either chromosomes 15 or 17 who nevertheless had juxtaposition …

A PML/RARA chimeric gene on chromosome 12 in a patient with acute promyelocytic leukemia (M4) associated with a new variant translocation: t(12;15;17)(q24;q24; …

A Bennour, I Tabka, YB Youssef, M Zaier, S Hizem… - Medical Oncology, 2013 - Springer
Acute promyelocytic leukemia (APL) is genetically characterized by a reciprocal
translocation between chromosomes 15 and 17, t (15; 17)(q22; q21), which results in the …

Acute promyelocytic leukemia with a rare PML exon 4/RARA exon 3 fusion transcript variant

SJ Oh, TS Park, JY Lee, YC Mun, CM Seong… - Acta …, 2013 - karger.com
The PML/RARA fusion transcript is generated by the reciprocal translocation t (15; 17)(q22;
q12) and derives from a prototypic gene fusion, which is important for diagnosis and …

Acute promyelocytic leukemia with PML-RARA fusion on i (17q) and therapy-related acute myeloid leukemia

GY Lee, S Christina, SL Tien, ABA Ghafar… - Cancer genetics and …, 2005 - Elsevier
We describe a patient with acute promyelocytic leukemia (APL) and the karyotype 46, XX, i
(17)(q10) with PML-RARA fusion gene detected by fluorescence in situ hybridization (FISH) …

Cytogenetic and molecular analysis of an unusual case of acute promyelocytic leukemia with at (15; 17; 17)(q22; q23; q21)

CA Tirado, V Golembiewski-Ruiz… - Cancer genetics and …, 2003 - Elsevier
We present a 52-year-old female with a clinical history of acute myelocytic leukemia,
probable acute promyelocytic leukemia (APL). Flow cytometry results were somewhat …

A new cytogenetic abnormality, t (2; 7)(q33; q36), in acute promyelocytic leukemia

S Owatari, K Uozumi, K Haraguchi, N Ohno… - Cancer genetics and …, 2007 - Elsevier
We report the case of a patient with acute promyelocytic leukemia (APL) carrying a novel
chromosomal abnormality, t (2; 7)(q33; q36). The 54-year-old woman was morphologically …

PML/RARα rearrangement in acute promyelocytic leukaemia with t(1;17) elucidated using fluorescence in situ hybridization

V Eclache, B Benzacken, G Le Roux… - British journal of …, 1997 - Wiley Online Library
Acute promyelocytic leukaemia (APL) is characterized by t (15; 17)(q22; q21) which results
in the formation of two chimaeric genes, PML/RARα and RARα/PML, thought to play a role in …