The tremendous biomedical potential of bacterial extracellular vesicles

J Xie, Q Li, F Haesebrouck, L Van Hoecke… - Trends in …, 2022 - cell.com
Bacterial extracellular vesicles (bEVs) are nano-sized, lipid membrane-delimited particles
filled with bacteria-derived components. They have important roles in the physiology and …

Bacterial membrane vesicles: biogenesis, immune regulation and pathogenesis

RD Pathirana, M Kaparakis‐Liaskos - Cellular microbiology, 2016 - Wiley Online Library
Outer membrane vesicles were first described approximately 50 years ago and for many
years were considered to be an artifact of bacterial growth. Since that initial discovery, it has …

Bacterial membrane vesicles, an overlooked environmental colloid: biology, environmental perspectives and applications

M Toyofuku, Y Tashiro, Y Hasegawa… - Advances in Colloid and …, 2015 - Elsevier
Phospholipid vesicles play important roles in biological systems. Bacteria are one of the
most abundant organisms on Earth, and bacterial membrane vesicles (MVs) were first …

Bacterial membrane vesicles as promising vaccine candidates

L Jiang, M Schinkel, M van Essen… - European Journal of …, 2019 - Elsevier
Abstract Both Gram-positive and Gram-negative bacteria can release nano-sized lipid
bilayered structures, known as membrane vesicles (MVs). These MVs play an important role …

Outer membrane vesicles for vaccination and targeted drug delivery

S Wang, J Gao, Z Wang - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are cell membrane‐derived compartments that spontaneously
secrete from a wide range of cells and tissues. EVs have shown to be the carriers in …

[HTML][HTML] Bacterial outer membrane vesicles as a candidate tumor vaccine platform

S Wang, J Guo, Y Bai, C Sun, Y Wu, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer represents a serious concern for human life and health. Due to drug resistance and
the easy metastasis of tumors, there is urgent need to develop new cancer treatment …

Bacterial outer membrane vesicles as a versatile tool in vaccine research and the fight against antimicrobial resistance

Z Zhu, F Antenucci, KR Villumsen, AM Bojesen - MBio, 2021 - Am Soc Microbiol
Gram-negative bacteria include a number of pathogens that cause disease in humans and
animals. Although antibiotics are still effective in treating a considerable range of infections …

[HTML][HTML] Outer membrane vesicles: A bacterial-derived vaccination system

LA Lieberman - Frontiers in Microbiology, 2022 - frontiersin.org
Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from
the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis …

[HTML][HTML] Biomimetic bacterial membrane vesicles for drug delivery applications

S Fazal, R Lee - Pharmaceutics, 2021 - mdpi.com
Numerous factors need to be considered to develop a nanodrug delivery system that is
biocompatible, non-toxic, easy to synthesize, cost-effective, and feasible for scale up over …

Immune modulation by bacterial outer membrane vesicles

M Kaparakis-Liaskos, RL Ferrero - Nature Reviews Immunology, 2015 - nature.com
Gram-negative bacteria shed extracellular outer membrane vesicles (OMVs) during their
normal growth both in vitro and in vivo. OMVs are spherical, bilayered membrane …