Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A

CP Montgomery, M Daniels, F Zhao… - Infection and …, 2014 - Am Soc Microbiol
Although many microbial infections elicit an adaptive immune response that can protect
against reinfection, it is generally thought that Staphylococcus aureus infections fail to …

[HTML][HTML] IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

JS Cho, EM Pietras, NC Garcia… - The Journal of …, 2010 - Am Soc Clin Investig
Staphylococcus aureus is the most common cause of skin and soft tissue infections, and
rapidly emerging antibiotic-resistant strains are creating a serious public health concern. If …

[HTML][HTML] The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens

KA Lacey, JA Geoghegan, RM McLoughlin - Pathogens, 2016 - mdpi.com
Staphylococcus aureus (S. aureus) causes the vast majority of skin and soft tissue infections
(SSTIs) in humans. S. aureus has become increasingly resistant to antibiotics and there is …

Nonredundant roles of interleukin-17A (IL-17A) and IL-22 in murine host defense against cutaneous and hematogenous infection due to methicillin-resistant …

LC Chan, S Chaili, SG Filler, K Barr, H Wang… - Infection and …, 2015 - Am Soc Microbiol
Staphylococcus aureus is the leading cause of skin and skin structure infections (SSSI) in
humans. Moreover, the high frequency of recurring SSSI due to S. aureus, particularly …

Protection against Staphylococcus aureus colonization and infection by B-and T-cell-mediated mechanisms

F Zhang, O Ledue, M Jun, C Goulart, R Malley, YJ Lu - MBio, 2018 - Am Soc Microbiol
Staphylococcus aureus is a major cause of morbidity and mortality worldwide. S. aureus
colonizes 20 to 80% of humans at any one time and causes a variety of illnesses. Strains …

[HTML][HTML] Staphylococcus aureus epicutaneous exposure drives skin inflammation via IL-36-mediated T cell responses

H Liu, NK Archer, CA Dillen, Y Wang, AG Ashbaugh… - Cell host & …, 2017 - cell.com
Staphylococcus aureus colonization contributes to skin inflammation in diseases such as
atopic dermatitis, but the signaling pathways involved are unclear. Herein, epicutaneous S …

Innate and adaptive immune responses against Staphylococcus aureus skin infections

S Krishna, LS Miller - Seminars in immunopathology, 2012 - Springer
Staphylococcus aureus is an important human pathogen that is responsible for the vast
majority of bacterial skin and soft tissue infections in humans. S. aureus can also become …

Innate immune memory contributes to host defense against recurrent skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus

LC Chan, S Chaili, SG Filler, LS Miller… - Infection and …, 2017 - Am Soc Microbiol
Staphylococcus aureus is the leading cause of skin and skin structure infections (SSSI). The
high frequency of recurring SSSI due to S. aureus, including methicillin-resistant S. aureus …

[HTML][HTML] Local Inflammation Exacerbates the Severity of Staphylococcus aureus Skin Infection

CP Montgomery, MD Daniels, F Zhao, B Spellberg… - PloS one, 2013 - journals.plos.org
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S.
aureus skin infection, we found that lesion size did not correlate with bacterial burden …

[HTML][HTML] Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection

JM Leyva-Castillo, M Das, J Kane, M Strakosha… - JCI insight, 2021 - ncbi.nlm.nih.gov
Superficial cutaneous Staphylococcus aureus (S. aureus) infection in humans can lead to
soft tissue infection, an important cause of morbidity and mortality. IL-17A production by skin …