Background Wound infections, due to biofilms, are a constant problem because of their
recalcitrant nature towards antibiotics. Appropriate antibiotic selection for the treatment of …

G. WIRTANEN, S. SALO, DG ALLISON, T. MATTILA‐SANDHOLM AND P. GILBERT. 1998.
Poloxamer F127 is a di‐block co‐polymer of polyoxyethylene and polyoxypropylene …

P. GILBERT, MV JONES, DG ALLISON, S. HEYS, T. MAIRA AND P. WOOD. 1998.
Poloxamer F127 is a non‐toxic, di‐block copolymer of polyoxyethylene and …

Objectives The targeted disruption of biofilms in chronic wounds is an important treatment
strategy and the subject of intense research. In the present study, an in vitro model of chronic …

Microbial biofilms have become increasingly recognized as a cause of wound chronicity.
There are several topical antimicrobial wound care products available for use; however …

ABSTRACT A new in vitro pharmacokinetic/pharmacodynamic simulator for bacterial
biofilms utilizing flow cell technology and confocal laser scanning microscopy is described …

Wound infections represent a major problem, particularly in patients with chronic wounds.
Bacteria in the wound exist mainly in the form of biofilms and are thus resistant to most …

Background Biofilm is known to be tolerant towards antibiotics and difficult to eradicate.
Numerous studies have reported minimum biofilm eradication concentration (MBEC) values …

Objective: To use in vitro biofilm models of wound bacterial isolates and compare the
biofilms produced for different combinations of wound bacterial species. Method: In vitro …

Despite the constantly increasing need for new antimicrobial agents, antibiotic drug
discovery and development seem to have greatly decelerated in recent years. Presented …