The shape and size effects of polycation functionalized silica nanoparticles on gene transfection
X Lin, N Zhao, P Yan, H Hu, FJ Xu - Acta biomaterialia, 2015 - Elsevier
Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …
viral gene carriers, owing to their controlled morphologies, potential of facile surface …
Size-dependent gene delivery of amine-modified silica nanoparticles
Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …
insights into the effect of particle size on gene transfection efficiency, amine-modified …
Recent advances in the rational design of silica-based nanoparticles for gene therapy
Gene therapy has attracted much attention in modern society and provides a promising
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …
Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro and in vivo
MNV Kumar, M Sameti, SS Mohapatra… - … of nanoscience and …, 2004 - ingentaconnect.com
The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …
Enhanced gene delivery by polyethyleneimine coated mesoporous silica nanoparticles
H Zarei, R Kazemi Oskuee… - Pharmaceutical …, 2019 - Taylor & Francis
Due to large surface area, tunable pore size, easy surface manipulation, and low-toxicity
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …
Poly-L-lysine-modified silica nanoparticles: a potential oral gene delivery system
Z Li, S Zhu, K Gan, Q Zhang, Z Zeng… - … of Nanoscience and …, 2005 - ingentaconnect.com
Poly-L-lysine-modified silica nanoparticles (PMS-NP) is a novel nonviral vector for gene
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …
[HTML][HTML] Silica-based gene delivery systems: From design to therapeutic applications
Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …
O-Carboxymethyl-chitosan/organosilica hybrid nanoparticles as non-viral vectors for gene delivery
Y Zhang, P Yin, X Zhao, J Wang, J Wang… - Materials Science and …, 2009 - Elsevier
Polymeric non-viral vectors, such as chitosan nanoparticles show good biocompatibility, but
low transfection efficiency. The objective of this study was to improve the transfection …
low transfection efficiency. The objective of this study was to improve the transfection …
A novel gene carrier based on amino-modified silica nanoparticles
X He, K Wang, W Tan, B Liu, X Lin, S Huang, D Li… - Chinese Science …, 2003 - Springer
Uniform-sized amino-modified silica nanoparticles have been prepared by the controlled
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …
[HTML][HTML] Biodegradable polymers grafted onto multifunctional mesoporous silica nanoparticles for gene delivery
EPF Nhavene, GF Andrade, JAQA Faria, DA Gomes… - ChemEngineering, 2018 - mdpi.com
Biodegradable polymer possesses significant potential for applications in different fields,
since flexibility gives rise to materials with great physical and mechanical property diversity …
since flexibility gives rise to materials with great physical and mechanical property diversity …