Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …

Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

Silica nanoparticles (SNPs) have attracted widespread attention as biocompatible and
efficient nanocarriers for gene delivery. The physicochemical properties of SNPs such as …

Gene therapy has attracted much attention in modern society and provides a promising
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …

The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

Due to large surface area, tunable pore size, easy surface manipulation, and low-toxicity
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …

Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …

Poly-L-lysine-modified silica nanoparticles (PMS-NP) is a novel nonviral vector for gene
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …

Polymeric non-viral vectors, such as chitosan nanoparticles show good biocompatibility, but
low transfection efficiency. The objective of this study was to improve the transfection …

Uniform-sized amino-modified silica nanoparticles have been prepared by the controlled
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …