Polysialic acid affects pathophysiological consequences of status epilepticus
A Pekcec, B Weinhold, R Gerardy-Schahn… - …, 2010 - journals.lww.com
Modulation of the neural cell adhesion molecule by the attachment of polysialic acid
residues through the polysialyl-transferase, ST8SiaIV, regulates neuronal plasticity and …
residues through the polysialyl-transferase, ST8SiaIV, regulates neuronal plasticity and …
Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain
SP Galuska, M Rollenhagen, M Kaup… - Proceedings of the …, 2010 - National Acad Sciences
Among the large set of cell surface glycan structures, the carbohydrate polymer polysialic
acid (polySia) plays an important role in vertebrate brain development and synaptic …
acid (polySia) plays an important role in vertebrate brain development and synaptic …
[HTML][HTML] Molecular dissection of the ST8Sia IV polysialyltransferase: distinct domains are required for neural cell adhesion molecule recognition and polysialylation
K Angata, D Chan, J Thibault, M Fukuda - Journal of Biological Chemistry, 2004 - ASBMB
Polysialic acid, a homopolymer of α2, 8-linked sialic acid expressed on the neural cell
adhesion molecule (NCAM), is thought to play critical roles in neural development. Two …
adhesion molecule (NCAM), is thought to play critical roles in neural development. Two …
[HTML][HTML] Biosynthesis and expression of polysialic acid on the neural cell adhesion molecule is predominantly directed by ST8Sia II/STX during in vitro neuronal …
N Kojima, M Kono, Y Yoshida, Y Tachida… - Journal of Biological …, 1996 - ASBMB
We have reported recently that ST8Sia II/STX as well as ST8Sia IV/PST-1 is a neural cell
adhesion molecule (NCAM)-specific polysialic acid (PSA) synthase (Kojima, N., Tachida, Y …
adhesion molecule (NCAM)-specific polysialic acid (PSA) synthase (Kojima, N., Tachida, Y …
[HTML][HTML] Association of polysialic acid serum levels with schizophrenia spectrum and bipolar disorder-related structural brain changes and hospitalization
Expression of polysialic acid (polySia) in the adult brain is enriched in areas of continuous
neurogenesis and plasticity such as the hippocampus. Genome-wide association studies …
neurogenesis and plasticity such as the hippocampus. Genome-wide association studies …
[HTML][HTML] Divergent evolution of the vertebrate polysialyltransferase Stx and Pst genes revealed by fish-to-mammal comparison
M Marx, E Rivera-Milla, K Stummeyer… - Developmental …, 2007 - Elsevier
Polysialic acid (PSA) is a developmentally regulated carbohydrate attached to the neural
cell adhesion molecule (NCAM). PSA is involved in dynamic processes like cell migration …
cell adhesion molecule (NCAM). PSA is involved in dynamic processes like cell migration …
Polysialic acid: three-dimensional structure, biosynthesis and function
M Mühlenhoff, M Eckhardt… - Current opinion in …, 1998 - Elsevier
Polysialic acid is a unique cell surface polysaccharide found in the capsule of neuroinvasive
bacteria and as a highly regulated post-translational modification of the neural cell adhesion …
bacteria and as a highly regulated post-translational modification of the neural cell adhesion …
[HTML][HTML] Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments
H Varbanov, S Jia, G Kochlamazashvili… - Neurobiology of …, 2023 - Elsevier
Dysregulated cortical expression of the neural cell adhesion molecule (NCAM) and deficits
of its associated polysialic acid (polySia) have been found in Alzheimer's disease and …
of its associated polysialic acid (polySia) have been found in Alzheimer's disease and …
NCAM and polysialyltransferase profiles match dopaminergic marker gene expression but polysialic acid is dispensable for development of the midbrain dopamine …
M Schiff, B Weinhold, C Grothe… - Journal of …, 2009 - Wiley Online Library
The modification of the neural cell adhesion molecule (NCAM) with polysialic acid plays a
pivotal role in the developing nervous system. Here we studied the expression and function …
pivotal role in the developing nervous system. Here we studied the expression and function …
[HTML][HTML] Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration
YMJ Al-Saraireh, M Sutherland, BR Springett… - PloS one, 2013 - journals.plos.org
Polysialic acid (polySia), an α-2, 8-glycosidically linked polymer of sialic acid, is a
developmentally regulated post-translational modification predominantly found on NCAM …
developmentally regulated post-translational modification predominantly found on NCAM …