Immune responses in tissues are constrained by the physiological properties of the tissue
involved. Tissue-resident memory T cells (TRM cells) are a recently discovered lineage of T …

Tissue-resident memory T cells (TRM) represent a heterogeneous T cell population with the
functionality of both effector and memory T cells. TRM express residence gene signatures …

Over the past decade, it has become clear that there is an important subset of memory T
cells that resides in tissues—tissue-resident memory T (TRM) cells. There is an emerging …

Abstract CD4+ and CD8+ T lymphocytes mediate most of the adaptive immune response
against tumors. Naïve T lymphocytes specific for tumor antigens are primed in lymph nodes …

Resident memory (TRM) cells are a distinct tissue-localized T cell lineage that is crucial for
protective immunity in peripheral tissues. While a great deal of effort has focused on defining …

Resident memory T cells (TRM) form a distinct type of T memory cells that stably resides in
tissues. TRM form an integral part of the immune sensing network and have the ability to …

CD8+ tissue resident memory T cells (TRM cells) are essential for immune defence against
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …

A novel population of memory CD8+ T cells called resident memory T cells (TRM) has been
identified based on their phenotype (CD103, CD69) and on their local tissue residency …

Tissue resident memory T cells (Trm) are a subset of memory T cells mainly described in
inflammation and infection settings. Their location in peripheral tissues, such as lungs, gut …

Following their activation and expansion in response to foreign threats, many T cells are
retained in peripheral tissues without recirculating in the blood. These tissue-resident CD8+ …