A series of recent studies in our laboratory have provided evidence that opioid peptides
powerfully suppress feline affective defense behavior at the level of the midbrain …

The effects of the methionine-enkephalin analog [D-Ala 2-Met 5]-enkephalinamide (DAME)
upon the threshold for affective defense behavior were determined following microinjections …

The effects of central infusion of naloxone into the midbrain periaqueductal gray (PAG) upon
predatory attack behavior in the cat were studied in 12 cats. Initially, quiet biting attack was …

The present study sought to identify specific opioid receptor subtypes involved in the
modulation of affective defense behavior (AD) at the level of the midbrain periaqueductal …

Adequate electrical stimulation of extreme lateral hypothalamic regions of healthy, non-
aggressive male cats was employed to produce aggression on live but anaesthetized rats …

The present study was designed to test the hypothesis that a major excitatory mechanism for
the expression of feline defensive rage behavior involves the medial nucleus of the …

Much evidence suggests that the midbrain periaqueductal gray region (PAG) plays a pivotal
role in mediating an animal's responses to threatening, stressful, or painful stimuli. Active …

Previous reports indicate that the midbrain periaqueductal gray and the central nucleus of
the amygdala are interconnected but the organization of these projections has not been …

Studies designed to determine the respective roles of substance P, excitatory amino acids,
and enkephalins in amygdaloid modulation of defensive rage behavior in the cat are …

In the studies presented in this article, we have described the role of opioid peptides in the
regulation of feline aggression. In the first study, stimulation via monopolar electrodes …