Abstract World Health Organization category 1 pulmonary hypertension (PH) is a
heterogeneous syndrome in which PH originates in the small pulmonary arteries and is …

Despite improved understanding of the pathobiology of pulmonary arterial hypertension
(PAH), it remains a severe and progressive disease, usually culminating in right heart …

Rationale: The complex pathologies associated with severe pulmonary arterial hypertension
(PAH) in humans have been a challenge to reproduce in mice due to the subtle phenotype …

Severe forms of pulmonary arterial hypertension (PAH) are characterized by various
degrees of remodeling of the pulmonary arterial vessels, which increases the pulmonary …

Following its initial description over a century ago, pulmonary arterial hypertension (PAH)
continues to challenge researchers committed to understanding its pathobiology and finding …

Pulmonary arterial hypertension (PAH) is a progressive pulmonary vasoproliferative
disorder characterized by the development of unique neointimal lesions, including …

At present, six groups of chronic pulmonary hypertension (PH) are described. Among these,
group 1 (and 1′) comprises a group of diverse diseases termed pulmonary arterial …

Pulmonary arterial hypertension (PAH) is a severe form of pulmonary hypertension that
combines multiple alterations of pulmonary arteries, including, in particular, thrombotic and …

Pulmonary arterial hypertension (PAH) is a serious pathological phenomenon with poor
prognosis, which is associated with morphological as well as hemodynamic alteration of the …

Pulmonary hypertension (PH) is a severe progressive disorder with an unclear etiology and
a poor prognosis. Current treatments can alleviate the symptoms and even revert the …