An evidence-based knowledgebase of pulmonary arterial hypertension to identify genes and pathways relevant to pathogenesis
Pulmonary arterial hypertension (PAH) is a major progressive form of pulmonary
hypertension (PH) with more than 4800 patients in the United States. In the last two …
hypertension (PH) with more than 4800 patients in the United States. In the last two …
Group 3 pulmonary hypertension: from bench to bedside
N Singh, P Dorfmüller, OA Shlobin… - Circulation …, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3
PH in the most recent classification system. Prevalence of these diseases is increasing over …
PH in the most recent classification system. Prevalence of these diseases is increasing over …
An official American Thoracic Society statement: pulmonary hypertension phenotypes
Background: Current classification of pulmonary hypertension (PH) is based on a relatively
simple combination of patient characteristics and hemodynamics. This limits customization …
simple combination of patient characteristics and hemodynamics. This limits customization …
The emergence of new therapeutic targets in pulmonary arterial hypertension: from now to the near future
S Malenfant, G Margaillan, JE Loehr… - Expert Review of …, 2013 - Taylor & Francis
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease that pathologically
increases pulmonary vascular resistance. Ultimately, this leads to right ventricular failure …
increases pulmonary vascular resistance. Ultimately, this leads to right ventricular failure …
Experimental and transgenic models of pulmonary hypertension
J West, A Hemnes - Comprehensive Physiology, 2011 - Wiley Online Library
Pulmonary hypertension in human patients can result from increased pulmonary vascular
tone, pressure transferred from the systemic circulation, dropout of small pulmonary vessels …
tone, pressure transferred from the systemic circulation, dropout of small pulmonary vessels …
Transcription factors and potential therapeutic targets for pulmonary hypertension
L Yang, N Wan, F Gong, X Wang, L Feng… - Frontiers in Cell and …, 2023 - frontiersin.org
Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive
pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary …
pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary …
Translating research into improved patient care in pulmonary arterial hypertension
S Bonnet, S Provencher, C Guignabert… - American journal of …, 2017 - atsjournals.org
We have witnessed significant advances in the management of pulmonary arterial
hypertension (PAH)(1), a rare and severe condition characterized by intense pulmonary …
hypertension (PAH)(1), a rare and severe condition characterized by intense pulmonary …
[HTML][HTML] Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid …
Pulmonary arterial hypertension (PAH) is a rare, life-threatening condition characterized by
dysregulated metabolism, pulmonary vascular remodeling, and loss of pulmonary vascular …
dysregulated metabolism, pulmonary vascular remodeling, and loss of pulmonary vascular …
New drugs and therapies in pulmonary arterial hypertension
Pulmonary arterial hypertension is a chronic, progressive disorder of the pulmonary
vasculature with associated pulmonary and cardiac remodeling. PAH was a uniformly fatal …
vasculature with associated pulmonary and cardiac remodeling. PAH was a uniformly fatal …
Molecular and genetic profiling for precision medicines in pulmonary arterial hypertension
S Fazal, M Bisserier, L Hadri - Cells, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare and chronic lung disease characterized by
progressive occlusion of the small pulmonary arteries, which is associated with structural …
progressive occlusion of the small pulmonary arteries, which is associated with structural …