The central role of metal coordination in selenium antioxidant activity

EE Battin, NR Perron, JL Brumaghim - Inorganic chemistry, 2006 - ACS Publications
Oxidative DNA damage occurs in vivo by hydroxyl radical generated in metal-mediated
Fenton-type reactions. Cell death and mutation caused by this DNA damage are implicated …

Involvement of Superoxide Dismutases in the Response of Escherichia coli to Selenium Oxides

M Bébien, G Lagniel, J Garin, D Touati… - Journal of …, 2002 - Am Soc Microbiol
Selenium can provoke contrasting effects on living organisms. It is an essential trace
element, and low concentrations have beneficial effects, such as the reduction of the …

Selenium: Significance, and outlook for supplementation

M Kieliszek, S Błażejak - Nutrition, 2013 - Elsevier
Selenium is a metalloid element with the atomic number 34. It is one of the elements that
determine the normal functioning of an organism; it has antioxidant properties and protects …

NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family

AD Ferguson, VM Labunskyy, DE Fomenko… - Journal of Biological …, 2006 - ASBMB
Selenium has significant health benefits, including potent cancer prevention activity and
roles in immune function and the male reproductive system. Selenium-containing proteins …

[图书][B] Selenium: its molecular biology and role in human health

DL Hatfield, MJ Berry, VN Gladyshev - 2011 - books.google.com
Many health benefits have been attributed to selenium that include preventing various forms
of cancer (eg, colon cancer, prostate cancer, lung cancer and liver cancer), heart disease …

Selenium: from cancer prevention to DNA damage

L Letavayová, V Vlčková, J Brozmanová - Toxicology, 2006 - Elsevier
Selenium (Se) is a dietary essential trace element with important biological roles.
Accumulating evidence indicates that Se compounds possess anticancer properties. Se is …

Synthesis and antioxidant properties of organoselenium compounds

R Mamgain, M Kostic, FV Singh - Current medicinal chemistry, 2023 - ingentaconnect.com
Background: The chemistry of organoselenium reagents provides an asset for organic
synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them …

Prooxidant mechanisms of selenium toxicity–a review

M Mézes, K Balogh - Acta Biologica Szegediensis, 2009 - 160.114.156.156
Selenium is an essential trace element in living organisms as integral part of seleno-
enzymes. However, excess amount of selenium is toxic for so-called non-accumulator …

New careers for antioxidants

DE Brash, PA Havre - … of the National Academy of Sciences, 2002 - National Acad Sciences
It is a remarkable fact that antioxidants are nontoxic compounds that reduce the incidence of
cancer. Antioxidant nutrients such as vitamin E, ß-carotene, lycopene, and selenium are …

Cell death caused by selenium deficiency and protective effect of antioxidants

Y Saito, Y Yoshida, T Akazawa, K Takahashi… - Journal of Biological …, 2003 - ASBMB
Selenium is an essential trace element and it is well known that selenium is necessary for
cell culture. However, the mechanism underlying the role of selenium in cellular proliferation …