Macrophages are key regulators of many organ systems, including innate and adaptive
immunity, systemic metabolism, hematopoiesis, vasculogenesis, malignancy, and …

Macrophages are unique cells for origin, heterogeneity and plasticity. At steady state most of
macrophages are derived from fetal sources and maintained in adulthood through self …

In terms of both phenotype and function, macrophages have remarkable heterogeneity,
which reflects the specialization of tissue-resident macrophages in microenvironments as …

Monocytes and macrophages provide the first line of defense against pathogens. They also
initiate acquired immunity by processing and presenting antigens and provide the …

Macrophages function as sentinel cells, which constantly monitor the host environment for
infection or injury. Macrophages have been shown to exhibit a spectrum of activated …

Macrophages are now routinely categorized into phenotypic subtypes based on gene
expression induced in response to cytokine and pathogen-derived stimulation. In the …

Monocytes and macrophages play critical roles in immune responses, tissue homeostasis
and disease progression. There are a number of functionally and phenotypically distinct …

Monocytes/macrophages are heterogeneous and versatile cells that could undergo their
phenotypically/functionally dynamic switch in response to the microenvironment signals …

Macrophage polarization refers to development of a specific phenotype important for tissue
homeostasis or host defense in response to environmental cues. Environmental factors that …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …