Recent progress of polymeric nanogels for gene delivery

R Kandil, OM Merkel - Current opinion in colloid & interface science, 2019 - Elsevier
With its nearly unrestricted possibilities, gene therapy attracts more and more significance in
modern-day research. The only issue still seeming to hold back its clinical success is the …

Oligonucleotide based nanogels for cancer therapeutics

H Hatami, N Rahiman, M Mohammadi - International Journal of Biological …, 2024 - Elsevier
Oligonucleotide-based nanogels, as nascent biomaterials, possess several unique
functional, structural, and physicochemical features with excellent drug-loading capacity and …

Carbohydrate-based nanogels as drug and gene delivery systems

S Uthaman, S Maya, R Jayakumar… - … of Nanoscience and …, 2014 - ingentaconnect.com
Nanogels are hydrogels with nanometer-scale three-dimensional networks of physically or
chemically cross-linked chains. Nanogels have attracted much interest in recent years for …

Nanogels for intracellular delivery of biotherapeutics

D Li, CF van Nostrum, E Mastrobattista… - Journal of Controlled …, 2017 - Elsevier
Many biomolecules, such as proteins and genes, are presently used as therapeutics.
However, their delivery to target sites inside cells is challenging because of their large …

Biodegradable and nontoxic nanogels as nonviral gene delivery systems

R Sunasee, P Wattanaarsakit, M Ahmed… - Bioconjugate …, 2012 - ACS Publications
The development of polymeric systems with tailored properties as nonviral gene carriers
continues to be a challenging and exciting field of research. We report here the synthesis …

Biodegradable polymer nanogels for drug/nucleic acid delivery

Y Li, D Maciel, J Rodrigues, X Shi, H Tomás - Chemical reviews, 2015 - ACS Publications
Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …

DNA nanogel for cancer therapy

X Zhang, W Yan, Z Song, S Asif, I Hussain… - Advanced …, 2023 - Wiley Online Library
DNA nanogel exhibits properties of both the DNA and hydrogel, for example, remarkable
biocompatibility, programmability, high drug loading capacity, and rapid stimuli‐responsive …

Preparation of cationic nanogels for nucleic acid delivery

SE Averick, E Paredes, A Irastorza… - …, 2012 - ACS Publications
Cationic nanogels with site-selected functionality were designed for the delivery of nucleic
acid payloads targeting numerous therapeutic applications. Functional cationic nanogels …

Nanogel functionalization: a versatile approach to meet the challenges of drug and gene delivery

E Mauri, G Perale, F Rossi - ACS Applied Nano Materials, 2018 - ACS Publications
The design of nanostructures carrying therapeutic molecules represents the new frontier in
the biological and medical fields. In particular, researchers have identified nanogels as …

Polymeric nanogels produced via inverse microemulsion polymerization as potential gene and antisense delivery agents

K McAllister, P Sazani, M Adam, MJ Cho… - Journal of the …, 2002 - ACS Publications
Polymeric nanogel vectors were developed for cellular gene and antisense delivery. Inverse
microemulsion polymerization was utilized to synthesize biocompatible nanogels with …