Recent progress of polymeric nanogels for gene delivery
R Kandil, OM Merkel - Current opinion in colloid & interface science, 2019 - Elsevier
With its nearly unrestricted possibilities, gene therapy attracts more and more significance in
modern-day research. The only issue still seeming to hold back its clinical success is the …
modern-day research. The only issue still seeming to hold back its clinical success is the …
Oligonucleotide based nanogels for cancer therapeutics
Oligonucleotide-based nanogels, as nascent biomaterials, possess several unique
functional, structural, and physicochemical features with excellent drug-loading capacity and …
functional, structural, and physicochemical features with excellent drug-loading capacity and …
Carbohydrate-based nanogels as drug and gene delivery systems
S Uthaman, S Maya, R Jayakumar… - … of Nanoscience and …, 2014 - ingentaconnect.com
Nanogels are hydrogels with nanometer-scale three-dimensional networks of physically or
chemically cross-linked chains. Nanogels have attracted much interest in recent years for …
chemically cross-linked chains. Nanogels have attracted much interest in recent years for …
Nanogels for intracellular delivery of biotherapeutics
D Li, CF van Nostrum, E Mastrobattista… - Journal of Controlled …, 2017 - Elsevier
Many biomolecules, such as proteins and genes, are presently used as therapeutics.
However, their delivery to target sites inside cells is challenging because of their large …
However, their delivery to target sites inside cells is challenging because of their large …
Biodegradable and nontoxic nanogels as nonviral gene delivery systems
The development of polymeric systems with tailored properties as nonviral gene carriers
continues to be a challenging and exciting field of research. We report here the synthesis …
continues to be a challenging and exciting field of research. We report here the synthesis …
Biodegradable polymer nanogels for drug/nucleic acid delivery
Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …
DNA nanogel for cancer therapy
X Zhang, W Yan, Z Song, S Asif, I Hussain… - Advanced …, 2023 - Wiley Online Library
DNA nanogel exhibits properties of both the DNA and hydrogel, for example, remarkable
biocompatibility, programmability, high drug loading capacity, and rapid stimuli‐responsive …
biocompatibility, programmability, high drug loading capacity, and rapid stimuli‐responsive …
Preparation of cationic nanogels for nucleic acid delivery
SE Averick, E Paredes, A Irastorza… - …, 2012 - ACS Publications
Cationic nanogels with site-selected functionality were designed for the delivery of nucleic
acid payloads targeting numerous therapeutic applications. Functional cationic nanogels …
acid payloads targeting numerous therapeutic applications. Functional cationic nanogels …
Nanogel functionalization: a versatile approach to meet the challenges of drug and gene delivery
The design of nanostructures carrying therapeutic molecules represents the new frontier in
the biological and medical fields. In particular, researchers have identified nanogels as …
the biological and medical fields. In particular, researchers have identified nanogels as …
Polymeric nanogels produced via inverse microemulsion polymerization as potential gene and antisense delivery agents
K McAllister, P Sazani, M Adam, MJ Cho… - Journal of the …, 2002 - ACS Publications
Polymeric nanogel vectors were developed for cellular gene and antisense delivery. Inverse
microemulsion polymerization was utilized to synthesize biocompatible nanogels with …
microemulsion polymerization was utilized to synthesize biocompatible nanogels with …