Progression of white matter hyperintensities of presumed vascular origin increases the risk of falls in older people

ML Callisaya, R Beare, T Phan… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Greater volume of cerebral white matter hyperintensities (WMH) of presumed
vascular origin may affect postural control and gait. WMH measured at one time point …

White matter hyperintensities are associated with falls in older people with dementia

ME Taylor, SR Lord, K Delbaere, W Wen… - Brain imaging and …, 2019 - Springer
Abstract White Matter Hyperintensities (WMHs) are associated with impaired gait, balance
and cognition and increased fall risk in cognitively healthy older people. However, few …

Brain white matter hyperintensities, executive dysfunction, instability, and falls in older people: a prospective cohort study

JJJ Zheng, SR Lord, JCT Close… - … Series A: Biomedical …, 2012 - academic.oup.com
Abstract Background. White matter hyperintensities (WMHs) are associated with fall risk
factors in older people including reduced cognitive functioning and impaired balance and …

White matter hyperintensity volume and impaired mobility among older adults

JZ Willey, N Scarmeas, FA Provenzano… - Journal of …, 2013 - Springer
Gait speed is associated with multiple adverse outcomes of aging. White matter
hyperintensities (WMH) on magnetic resonance imaging (MRI) have been associated with …

Rapid buildup of brain white matter hyperintensities over 4 years linked to ambulatory blood pressure, mobility, cognition, and depression in old persons

L Wolfson, DB Wakefield, N Moscufo… - … Series A: Biomedical …, 2013 - academic.oup.com
Background. Brain white matter hyperintensities (WMH) are associated with functional
decline in older people. We performed a 4-year cohort study examining progression of …

Increased risk of death in community-dwelling older people with white matter hyperintensities on MRI

KA Kerber, GT Whitman, DL Brown… - Journal of the neurological …, 2006 - Elsevier
BACKGROUND: Previous studies in subjects with a history of stroke have shown that white
matter hyperintensities (WMH) on MRI are associated with increased risk of death. However …

Cerebral white matter lesions, gait, and the risk of incident falls: a prospective population-based study

V Srikanth, R Beare, L Blizzard, T Phan, J Stapleton… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—The association between cerebral white matter lesions (WMLs)
and the risk of falls in older people is uncertain, with no supporting prospective evidence …

The correlation between white matter hyperintensity and balance disorder and fall risk: An observational, prospective cohort study

DC Shen, SL Wu, YZ Shi, S Wang… - Chronic Diseases and …, 2016 - mednexus.org
Objective: The presence of an association between white matter hyperintensity (WMH) and
the risk of falls in older people is uncertain, with little supporting prospective evidence …

Effect of normal aging versus hypertension, abnormal body mass index, and diabetes mellitus on white matter hyperintensity volume

KS King, RM Peshock, HC Rossetti, RW McColl… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—The natural history of white matter hyperintensity (WMH)
progression resulting from normal aging versus comorbid vascular insults remains unclear …

Mind the gaps: functional networks disrupted by white matter hyperintensities are associated with greater falls risk

RA Crockett, CL Hsu, E Dao, R Tam, W Alkeridy… - Neurobiology of …, 2022 - Elsevier
White matter hyperintensities (WMH) are associated with greater falls risk and slow gait
speed. Whether these deficits are caused by the disruption of large-scale functional …