[引用][C] Airway and systemic effects of inhaled corticosteroids in asthma: dose response relationship

BJ Lipworth - Pulmonary pharmacology, 1996 - Elsevier
For those patients who are not controlled on doses antiinflammatory activity. In this respect
FP, BUD of inhaled corticosteroid up to 1000 g/day, there is and BDP (via its active …

Clinical pharmacology of corticosteroids in bronchial asthma

BJ Lipworth - Pharmacology & therapeutics, 1993 - Elsevier
It is now recognised that suppression of the inflammatory cascade should be the
cornerstone of management in bronchial asthma. Inhaled corticosteroids are the most …

[引用][C] The place of high-dose inhaled corticosteroids in asthma therapy

MJ Smith - Drugs, 1987 - Springer
Inhaled corticosteroid therapy is well established as an effective form of maintenance
treatment in asthma and in conventional dosage has the advantage of avoiding the systemic …

Therapeutic index of inhaled corticosteroids in asthma: A dose–response comparison on airway hyperresponsiveness and adrenal axis suppression

P Daley‐Yates, N Brealey, S Thomas… - British Journal of …, 2021 - Wiley Online Library
Aims To compare the airway potency, systemic activity and therapeutic index of three
inhaled corticosteroids that differ in glucocorticoid receptor binding affinity, physicochemical …

Inhaled corticosteroids—their present and future role in the management of asthma

P König - Journal of allergy and clinical immunology, 1988 - Elsevier
Inhaled corticosteroids have been used successfully in the management of asthma for the
last 16 years,'ever since the discovery of agents with a favorable ratio of topical versus …

Establishing a therapeutic index for the inhaled corticosteroids: part I: pharmacokinetic/pharmacodynamic comparison of the inhaled corticosteroids

HW Kelly - Journal of allergy and clinical immunology, 1998 - Elsevier
The inhaled corticosteroids contain physicochemical differences that alter both
glucocorticoid receptor-binding characteristics and the pharmacokinetic variables of these …

Comparative studies of inhaled corticosteroids in asthma

R Beasley, PJ Sterk, HAM Kerstjens… - European Respiratory …, 2001 - Eur Respiratory Soc
With inhaled corticosteroids being the mainstay of anti-inflammatory treatment in asthma, it is
necessary to determine the comparative efficacy and safety of different corticosteroids …

The use of corticosteroids in the treatment of asthma

SL Spector - Chest, 1985 - journal.chestnet.org
"~ Then corticosteroids were first introduced for the treat-~" ment of asthma, they were hailed
as miracle drugs. As experience was extended, so was the appreciation of the myriad side …

The mechanism of action of corticosteroids in asthma

IK Taylor, RJ Shaw - Respiratory medicine, 1993 - Elsevier
The cardinal features of bronchial asthma are reversible airways obstruction, airway
inflammation and heightened bronchial responsiveness to a variety of unrelated stimuli …

Comparison of inhaled corticosteroids

HW Kelly - Annals of Pharmacotherapy, 1998 - journals.sagepub.com
OBJECTIVE: To review the comparative studies evaluating both efficacy and safety of
inhaled corticosteroids in the management of asthma. Specifically, comparative clinical trials …