Nanomedicinal strategies as emerging therapeutic avenues to treat and manage cerebral ischemia

S Fatima, SN Quadri, S Parveen, S Beg… - CNS & Neurological …, 2021 - ingentaconnect.com
Amongst the various diseases on a global scale, the second leading cause of mortality and
morbidity is ischemic stroke due to the unavailability of an effective therapy. With the growing …

Nanotechnology based diagnostic and therapeutic strategies for neuroscience with special emphasis on ischemic stroke

SB Nair, A Dileep, GK Rajanikant - Current medicinal chemistry, 2012 - ingentaconnect.com
Ischemic stroke is the second leading cause of death and long-term disability worldwide, for
which no effective therapies are available. The increasing prevalence of ischemic stroke and …

Progresses and prospects of neuroprotective agents-loaded nanoparticles and biomimetic material in ischemic stroke

J Chen, J Jin, K Li, L Shi, X Wen, F Fang - Frontiers in Cellular …, 2022 - frontiersin.org
Ischemic stroke remains the leading cause of death and disability, while the main
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …

Advanced nano drug delivery systems for neuroprotection against ischemic stroke

C Xie, J Liao, N Zhang, Y Sun, Y Li, L Xiong… - Chinese Chemical …, 2023 - Elsevier
Ischemic stroke (IS) represents a significant threat to brain health due to its elevated
mortality and disability rates. The efficacy of small-molecule neuroprotective agents has …

Nanomedicines, an emerging therapeutic regimen for treatment of ischemic cerebral stroke: A review

W Chen, L Jiang, Y Hu, G Fang, B Yang, J Li… - Journal of Controlled …, 2021 - Elsevier
Owing to its intricate pathophysiology, cerebral stroke is a serious medical condition caused
by interruption or obstruction of blood supply (blockage of vasculature) to the brain tissues …

Advances in nanomedicines: a promising therapeutic strategy for ischemic cerebral stroke treatment

J Li, F Xie, X Ma - Nanomedicine, 2024 - Taylor & Francis
Ischemic stroke, prevalent among the elderly, necessitates attention to reperfusion injury
post treatment. Limited drug access to the brain, owing to the blood–brain barrier, restricts …

Recent advances in nanomaterials for diagnosis, treatments, and neurorestoration in ischemic stroke

X Lin, N Li, H Tang - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Stroke is a major public health issue, corresponding to the second cause of mortality and the
first cause of severe disability. Ischemic stroke is the most common type of stroke …

Advanced Nano-Drug Delivery Systems in the Treatment of Ischemic Stroke

J Zhang, Z Chen, Q Chen - Molecules, 2024 - mdpi.com
In recent years, the frequency of strokes has been on the rise year by year and has become
the second leading cause of death around the world, which is characterized by a high …

Nanomedicines and stroke: Toward translational research

A Gaudin, K Andrieux, P Couvreur - Journal of Drug Delivery Science and …, 2015 - Elsevier
Since their introduction in the late 60′, nanotechnologies applied to medicine, called
nanomedicines, are believed to have the potential to be the mankind's first “giant step” …

[HTML][HTML] Recent advances in nanomedicines for the treatment of ischemic stroke

C Li, T Sun, C Jiang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Ischemic stroke is a cerebrovascular disease normally caused by interrupted blood supply to
the brain. Ischemia would initiate the cascade reaction consisted of multiple biochemical …