Irritable bowel syndrome (IBS) is a common gastrointestinal disorder in which the underlying
pathophysiology is poorly understood; however, increased intestinal permeability in …

Based on a systematic PubMed search, this short review addresses why intestinal
permeability may be important in the pathobiology of irritable bowel syndrome (IBS), the …

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal ailments among
those seeking health care for gastrointestinal disorders. Despite its prevalence, IBS …

OBJECTIVES Irritable bowel syndrome (IBS) is a heterogeneous condition and defined
according to symptoms. Low-grade inflammation has been associated with IBS, particularly …

Background Alterations in gastrointestinal (GI) permeability and immune measures are
present in some patients with irritable bowel syndrome (IBS) but the relationship to …

Background/Aims: Defective epithelial barrier has been implicated in the pathogenesis of
irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was …

Visceral hypersensitivity is currently considered a key pathophysiological mechanism
involved in pain perception in large subgroups of patients with functional gastrointestinal …

Background and Aim: Irritable bowel syndrome (IBS) is a complex and heterogeneous
disorder. Sensory, motor and barrier dysfunctions are the key physiological endophenotypes …

BACKGROUND/AIMS Visceral hypersensitivity is a feature of the irritable bowel syndrome
(IBS). Postprandial symptoms are common in these patients. The effects of nutrients on …

BACKGROUND AND AIMS Enhanced visceral sensitivity following a transient inflammatory
process in the gut has been postulated as an aetiological mechanism of irritable bowel …