Identification of Potential Inhibitors for Beta-Lactamase in Methicillin-Resistant Staphylococcus aureus from Flavonoids Using a Computational Drug Discovery …

A Abdollahian, M Hazhirkamal, M Taheri… - Letters in Drug …, 2023 - ingentaconnect.com
Background: Staphylococcus aureus (S. aureus) is a Gram-positive bacterium causing a
wide range of human infections, leading to life-threatening invasive disorders …

Identification of Phytochemicals with Inhibitory Potential Against Beta-lactamase Enzymes via Computer-aided Approach

GC Nwokebu, AB Adesina, CN Isibor, SA Aigbepue… - Bioorganic …, 2024 - Elsevier
Introduction Antibacterial drugs have been widely used for the past century to treat diseases,
but their efficacy has been limited by multi-resistant pathogens, particularly those that utilize …

[HTML][HTML] In silico study of inhibition effects of phytocompounds from four medicinal plants against the Staphylococcus aureus β-lactamase

F Etminani, A Etminani, SO Hasson, HK Judi… - Informatics in Medicine …, 2023 - Elsevier
Introduction This study aimed to evaluate new Staphylococcus aureus β-lactamase
inhibitors from medicinal plants Rosmarinus officinalis, Ocimum basilicum, Eucalyptus …

Insight into the screening of potential beta-lactamase inhibitors as anti-bacterial chemical agents through pharmacoinformatics study

P Parida, S Bhowmick, A Saha… - Journal of Biomolecular …, 2021 - Taylor & Francis
Drug resistance is an unsolved and major concern in the bacterial infection. Continuous
development of drug-resistance to the antibiotics exponentially rises the danger of bacterial …

In Silico Method for the Screening of Phytochemicals against Methicillin‐Resistant Staphylococcus Aureus

R Tabassum, S Kousar, G Mustafa… - BioMed Research …, 2023 - Wiley Online Library
Methicillin‐resistant Staphylococcus aureus (MRSA) has evolved resistance even against
the last resort β‐lactam antibiotics. This is because of the acquisition of an additional …

Enhancing bactericidal strategy with selected aromatic compounds: in vitro and in silico study

A Oztekin, K Karagoz, S Adem… - Journal of Biomolecular …, 2022 - Taylor & Francis
Abstract β-Lactamases are enzymes that catalyze the hydrolysis of the β-lactam ring,
resulting in loss of function in β-lactam antibiotics. In this report, the inhibition of β-lactamase …

Molecular Drug Docking of Multi Drug Resistant Antibiotics (Gentamicin, Linezolid and Norfloxacin) with Staphylococcus aureus C0673 by Implementing …

H Grace, D Leelavathi… - International Journal of …, 2024 - search.ebscohost.com
Background: Staphylococcus aureus is an adaptive and versatile microorganism that can
cause a wide range of ailments, from intense and short-lived infections to persistent …

Molecular docking and simulation studies of flavonoid compounds against PBP-2a of methicillin‐resistant Staphylococcus aureus

AK Verma, SF Ahmed, MS Hossain… - Journal of …, 2022 - Taylor & Francis
Abstract Methicillin-Resistant Staphylococcus aureus (MRSA), a pathogenic bacterium that
causes life-threatening outbreaks such as community-onset and nosocomial infections as …

In-Silico molecular screening of natural compounds as a potential therapeutic inhibitor for Methicillin-resistant Staphylococcus aureus inhibition

P Nandhini, PK Gupta, AK Mahapatra, AP Das… - Chemico-Biological …, 2023 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is a life-threatening superbug causing
infectious diseases such as pneumonia, endocarditis, osteomyelitis, etc. Conventional …

Methicillin‐Resistant Staphylococcus aureus: Docking‐Based Virtual Screening and Molecular Dynamics Simulations to Identify Potential Penicillin‐Binding Protein …

M Masumi, F Noormohammadi… - International journal …, 2022 - Wiley Online Library
Staphylococcus aureus (S. aureus) is responsible for several disorders including skin and
soft tissue infections, bacteremia, pulmonary infections, septic arthritis, osteomyelitis …