The extracellular pigment epithelium-derived factor (PEDF) displays retina survival activity
by interacting with receptor proteins on cell surfaces. We have previously reported that …

Pigment epithelium-derived factor (PEDF), a multifunctional protein, acts in retinal
differentiation, survival and maintenance by interacting with high affinity receptors on the …

The cytoprotective effects of pigment epithelium-derived factor (PEDF) require interactions
between an as of a yet undefined region with a distinct ectodomain on the PEDF receptor …

Pigment epithelium-derived factor (PEDF) is involved in signal transduction cascades
necessary for protection of the retina. The interaction between PEDF and retinal cells elicits …

Pigment epithelium-derived factor (PEDF) is an extracellular multifunctional protein
belonging to the serpin superfamily with demonstrable neurotrophic, gliastatic …

Pigment epithelium-derived factor (PEDF) can delay and prevent the death of
photoreceptors in vivo. We investigated the survival activity of PEDF on cone photoreceptor …

AMD (age-related macular degeneration) is a neurodegenerative disease causing
irreversible central blindness in the elderly. Apoptosis and inflammation play important roles …

Pigment epithelium‐derived factor (PEDF) is a cytoprotective protein for the retina. We
hypothesize that this protein acts on neuronal survival and differentiation of photoreceptor …

Calcium ions play a critical role in neuronal cell death. Pigment epithelium-derived factor
(PEDF) is a promising neuroprotective protein for photoreceptor cells but the mechanisms …

Pigment epithelium-derived factor (PEDF) is a 50-kDa protein encoded by a single gene that
shows strong conservation across phyla from fish to mammals. It is secreted by the retinal …