[PDF][PDF] I-23: Ahmad Rami Ayoun Alsoud Simultaneous Assessment of Time-to-positivity and Colony-forming Unit in tuberculosis patients under high-dose rifampicin …
RA Alsoud, RJ Svensson, EM Svensson… - PAGE2019 Poster … - m.page-meeting.org
Objectives: Colony forming unit (CFU) counting on solid agar has been used for more than
three decades to measure anti-tuberculosis (TB) drug activity in sputum samples before …
three decades to measure anti-tuberculosis (TB) drug activity in sputum samples before …
The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially …
Objectives The relationship between cfu and Mycobacterial Growth Indicator Tube (MGIT)
time to positivity (TTP) is uncertain. We attempted to understand this relationship and create …
time to positivity (TTP) is uncertain. We attempted to understand this relationship and create …
Comparison of time to positive and colony counting in an early bactericidal activity study of anti-tuberculosis treatment
CM Bark, P Gitta, S Ogwang, M Nsereko… - … of tuberculosis and …, 2013 - ingentaconnect.com
SETTING: Patients with smear-positive, newly diagnosed pulmonary tuberculosis (TB)
presenting to the out-patient TB clinic in Kampala, Uganda. OBJECTIVE: To compare colony …
presenting to the out-patient TB clinic in Kampala, Uganda. OBJECTIVE: To compare colony …
Pre-treatment mycobacterial sputum load influences individual on-treatment measurements
AH Diacon, L van der Merwe, AM Demers… - Tuberculosis, 2014 - Elsevier
Time to culture positivity (TTP) in liquid medium is now widely available as a measure of
viable mycobacterial sputum load. TTP correlates well with and could replace colony …
viable mycobacterial sputum load. TTP correlates well with and could replace colony …
[HTML][HTML] Analysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification
Abstract The BACTEC Mycobacteria Growth Indicator Tube (MGIT) machine is the standard
globally for detecting viable mycobacteria in patients' sputum. Samples are observed for no …
globally for detecting viable mycobacteria in patients' sputum. Samples are observed for no …
[HTML][HTML] Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development
R Ayoun Alsoud, RJ Svensson, EM Svensson… - Frontiers in …, 2023 - frontiersin.org
Biomarkers are quantifiable characteristics of biological processes. In Mycobacterium
tuberculosis, common biomarkers used in clinical drug development are colony forming unit …
tuberculosis, common biomarkers used in clinical drug development are colony forming unit …
[HTML][HTML] IP-10 kinetics in the first week of therapy are strongly associated with bacteriological confirmation of tuberculosis diagnosis in HIV-infected patients
AL García-Basteiro, E Mambuque, A den Hertog… - Scientific reports, 2017 - nature.com
Simple effective tools to monitor the long treatment of tuberculosis (TB) are lacking. Easily
measured host derived biomarkers have been identified but need to be validated in larger …
measured host derived biomarkers have been identified but need to be validated in larger …
Time to detection of Mycobacterium tuberculosis in BACTEC systems as a viable alternative to colony counting
C Pheiffer, NM Carroll, N Beyers… - … of Tuberculosis and …, 2008 - ingentaconnect.com
OBJECTIVE: To investigate whether time to detection (TTD) of Mycobacterium tuberculosis
in BACTEC Mycobacteria Growth Indicator Tube (MGIT) 960 and BACTEC 460 TB systems …
in BACTEC Mycobacteria Growth Indicator Tube (MGIT) 960 and BACTEC 460 TB systems …
Time to detection of the growth of Mycobacterium tuberculosis in MGIT 960 for determining the early bactericidal activity of antituberculosis agents
AH Diacon, JS Maritz, A Venter, PD Van Helden… - European journal of …, 2010 - Springer
Abstract Evaluation of early bactericidal activity (EBA) by the determination of a fall in viable
colony-forming units (CFU) of Mycobacterium tuberculosis in sputum is a first step in the …
colony-forming units (CFU) of Mycobacterium tuberculosis in sputum is a first step in the …
Longitudinal model-based biomarker analysis of exposure-response relationships in adults with pulmonary tuberculosis
AD Gewitz, BP Solans, WR Mac Kenzie… - Antimicrobial agents …, 2021 - Am Soc Microbiol
The identification of sensitive, specific, and reliable biomarkers that can be quantified in the
early phases of tuberculosis treatment and predictive of long-term outcome is key for the …
early phases of tuberculosis treatment and predictive of long-term outcome is key for the …