[HTML][HTML] Cytokine kinetics in the first week of tuberculosis therapy as a tool to confirm a clinical diagnosis and guide therapy
AL den Hertog, M Montero-Martín, RL Saunders… - PLoS …, 2015 - journals.plos.org
Background Many patients treated for tuberculosis (TB) in low and middle income countries
are treated based on clinical suspicion without bacteriological confirmation. This is often due …
are treated based on clinical suspicion without bacteriological confirmation. This is often due …
[HTML][HTML] Incipient tuberculosis: a comprehensive overview
S Rotundo, MT Tassone, F Serapide, A Russo… - Infection, 2024 - Springer
In the context of the evolving global health landscape shaped by the COVID-19 pandemic,
tuberculosis (TB) is gaining renewed attention as a reemerging threat even in low-endemic …
tuberculosis (TB) is gaining renewed attention as a reemerging threat even in low-endemic …
[HTML][HTML] A novel blood-based assay for treatment monitoring of tuberculosis
AJ Zimmer, SG Schumacher, E Södersten… - BMC Research …, 2021 - Springer
Objectives A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has
been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA …
been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA …
[HTML][HTML] Do Xpert MTB/RIF cycle threshold values provide information about patient delays for tuberculosis diagnosis?
W Ssengooba, D Respeito, E Mambuque, S Blanco… - PLoS …, 2016 - journals.plos.org
Introduction Early diagnosis and initiation to appropriate treatment is vital for tuberculosis
(TB) control. The XpertMTB/RIF (Xpert) assay offers rapid TB diagnosis and quantitative …
(TB) control. The XpertMTB/RIF (Xpert) assay offers rapid TB diagnosis and quantitative …
[PDF][PDF] The Quest for Potential Host Blood Biomarkers for Tuberculosis Diagnosis, Severity and Treatment Effect: Are we there Yet?
Published: May 21, 2019 Tuberculosis (TB) continues to have a major impact on global
health. As per WHO report in 2017 [1], an estimated 10 million people developed …
health. As per WHO report in 2017 [1], an estimated 10 million people developed …
[HTML][HTML] Time to Detection of Growth for Mycobacterium tuberculosis in a Low Incidence Area
R Vongthilath-Moeung, A Poncet, G Renzi… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Diagnosis of Mycobacterium tuberculosis (MTB) infection can be confirmed by
Xpert assays within hours. However, when sample size does not allow performing both …
Xpert assays within hours. However, when sample size does not allow performing both …
[HTML][HTML] Clinical evaluation of the novel molecular bacterial load assay for real-time monitoring of tuberculosis treatment response
Background Monitoring the treatment of tuberculosis (TB) relies on less sensitive smear
microscopy (SM) and culture methods which are very slow. We evaluated the novel …
microscopy (SM) and culture methods which are very slow. We evaluated the novel …
Biomarkers to predict Tuberculosis treatment response
I Boshielo - wiredspace.wits.ac.za
Tuberculosis (TB) is a chronic disease caused by Mycobacterium tuberculosis (Mtb). Despite
the implementation of multifaceted TB prevention and control efforts, a significant number of …
the implementation of multifaceted TB prevention and control efforts, a significant number of …
Early Microbiologic Markers of Pulmonary Tuberculosis Treatment Outcomes
MS Paradkar, NN Pradhan, S Balaji… - Annals of the …, 2023 - atsjournals.org
Rationale: Earlier biomarkers of pulmonary tuberculosis (PTB) treatment outcomes are
critical to monitor shortened anti-TB treatment (ATT). Objectives: To identify early …
critical to monitor shortened anti-TB treatment (ATT). Objectives: To identify early …
Exploring a combined biomarker for tuberculosis treatment response: protocol for a prospective observational cohort study
Introduction An improved understanding of factors explaining tuberculosis (TB) treatment
response is urgently needed to help clinicians optimise and personalise treatment and …
response is urgently needed to help clinicians optimise and personalise treatment and …