Polymorphism of AXIN2, a component of Wnt signaling, has been shown to play a role in
tumorigenesis and dysregulated in cancer cells. In order to find out if AXIN2 polymorphism is …

The Wnt signaling pathway plays a crucial role in human cancer development, and axis
inhibition protein 2 (Axin2) is a master scaffold protein involved in Wnt signaling. Axin2 …

The product of AXIN2, a component of Wnt signalling, plays a role in tumorigenesis and is
dysregulated in cancer cells. In order to determine whether the AXIN2 polymorphism is a risk …

Plenty of epidemiological studies have assessed the effects of AXIN2 polymorphisms on the
risk of developing cancer, but the available results were somewhat inconclusive. Odds ratios …

Background Many epidemiological studies have investigated association of AXIN2 variants
on overall cancer risks; however, the available results remain inconsistent. Methods An …

Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms
in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes …

Background Numerous studies have reported the correlation between AXIN2 polymorphism
and cancer risk, but the results seem not consistent. In order to get an overall, accurate and …

Background Variants in the axis inhibition 2 (AXIN2) gene might alter the protein's structure
or function or create a multiprotein destruction complex in the Wnt signaling pathway and …

Background & objectives: Ovarian cancer is the most common female reproductive cancer
which is caused due to the malignant transformation of ovarian cells. This type of cancer is …

Several studies have reported an association between− 148 C/T polymorphism of Axis
inhibition protein 2 (Axin2) and cancer risk; however, the results are inconsistent. In this …