Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies

F Barbieri, M Albertelli, F Grillo, A Mohamed… - Drug discovery today, 2014 - Elsevier
Highlights•Novel therapeutic options are crucially needed for relatively rare but deadly
NETs.•Somatostatin analogs control tumor growth and symptoms in selected …

[HTML][HTML] Novel therapeutic approaches and mechanisms in neuroendocrine tumors: the role of targeted agents

G Papaxoinis, K Syrigos, MW Saif - Discovery Medicine, 2016 - discoverymedicine.com
Low-intermediate grade neuroendocrine tumors (NETs) are usually slow-growing cancers
with a clinical course spanning few to several years managed with active surveillance …

[HTML][HTML] How I treat neuroendocrine tumours

B Kiesewetter, M Raderer - ESMO open, 2020 - Elsevier
Neuroendocrine tumours (NETs) constitute a heterogeneous group of neoplasms
characterised by variable endocrine activity and somatostatin receptor expression, with the …

Translation of molecular pathways into clinical trials of neuroendocrine tumors

M Pavel - Neuroendocrinology, 2013 - karger.com
Current treatment options for neuroendocrine tumors (NET) include somatostatin analogs,
interferon-α, peptide receptor-targeted therapy and cytotoxic chemotherapy. Most patients …

A systematic review of management of neuroendocrine tumors: an experience from a tertiary care centre from India

R Kapoor, T Bhattacharyya, R Gupta… - Clinical Cancer …, 2014 - ccij-online.org
Neuroendocrine tumors (NETs) encompass a heterogeneous group of tumors
demonstrating varied clinical behavior. The field has recently witnessed several important …

New drugs in the therapy of neuroendocrine tumors

S Grozinsky-Glasberg, DJ Gross - Journal of endocrinological investigation, 2012 - Springer
Neuroendocrine tumors (NET) are a rare and heterogeneous group of neoplasms of a
relatively indolent nature whose incidence and prevalence are increasing. Despite the …

Targeted cancer therapy: what's new in the field of neuroendocrine neoplasms?

A La Salvia, P Espinosa-Olarte, MDC Riesco-Martinez… - Cancers, 2021 - mdpi.com
Simple Summary Neuroendocrine neoplasms are highly heterogeneous tumors in terms of
primary origin, molecular landscape, clinical presentation and behavior. To date, several …

The evolving landscape of neuroendocrine tumors

EK Bergsland - Seminars in Oncology, 2013 - Elsevier
Neuroendocrine tumors (NET) encompass a heterogeneous group of tumors demonstrating
varied clinical behavior. The field has recently witnessed several important developments …

Drug development in neuroendocrine tumors: what is on the horizon?

A Garcia-Alvarez, J Hernando Cubero… - … Treatment Options in …, 2021 - Springer
Opinion statement Neuroendocrine neoplasms (NENs) constitute a heterogenous group of
malignancies. Translational research into NEN cell biology is the cornerstone for drug …

Therapy of patients with neuroendocrine neoplasia—evidence-based approaches and new horizons

RA Bundschuh, B Habacha, S Lütje… - Journal of Clinical …, 2019 - mdpi.com
Neuroendocrine tumors (NETs) show low but increasing incidence and originate in multiple
organs, including the pancreas, midgut, caecum, rectum, appendix, colon, and lungs. Due to …