A diet that is high in fat can lead to obesity and various other metabolic issues, like type II
diabetes, cardiovascular disease, and non-alcoholic fatty liver disease. Interestingly, a diet …

A diet high in fat induces adiposity and obesity, and chronic feeding can lead to multiple
metabolic complications, including type II diabetes, non-alcoholic fatty liver disease, and …

We have previously demonstrated that the glucocorticoid receptor β (GRβ) isoform induces
hepatic steatosis in mice fed a normal chow diet. The GRβ isoform inhibits the glucocorticoid …

Glucocorticoids (GCs) regulate energy supply in response to stress by increasing hepatic
gluconeogenesis during fasting. Long-term GC treatment induces hepatic steatosis and …

Glucocorticoid hormones (GCs) are important regulators of lipid metabolism, promoting
lipolysis with acute treatment but lipogenesis with chronic exposure. Conventional wisdom …

Glucocorticoids are steroid hormones that play critical and complex roles in the regulation of
triglyceride (TG) homeostasis. Depending on physiological states, glucocorticoids can …

Objective The critical role of adipose tissue in energy and nutrient homeostasis is influenced
by many external factors, including overnutrition, inflammation, and exogenous hormones …

The glucocorticoids bind and activate both the glucocorticoid receptor (GR) as well as the
mineralocorticoid receptor in adipocytes. Despite several studies to determine the function of …

Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during
stress, such as fasting and starvation, in order to maintain plasma glucose levels. Excess …

Glucocorticoids (GCs) and their cognate, intracellular receptor, the glucocorticoid receptor
(GR) have been characterized as critical checkpoints in the hormonal control of energy …