[HTML][HTML] Transcription factor Nrf2 as a potential therapeutic target for COVID-19
Y Wang, J Ma, Y Jiang - Cell Stress and Chaperones, 2023 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) is caused by a novel severe acute
respiratory syndrome (SARS)–like coronavirus (SARS-CoV-2). Critically ill patients with …
respiratory syndrome (SARS)–like coronavirus (SARS-CoV-2). Critically ill patients with …
[HTML][HTML] SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic caused by a novel
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …
The possible role of nuclear factor erythroid‐2‐related factor 2 activators in the management of Covid‐19
HM Al‐kuraishy, AI Al‐Gareeb… - … of Biochemical and …, 2024 - Wiley Online Library
COVID‐19 is caused by a novel SARS‐CoV‐2 leading to pulmonary and extra‐pulmonary
manifestations due to oxidative stress (OS) development and hyperinflammation. COVID‐19 …
manifestations due to oxidative stress (OS) development and hyperinflammation. COVID‐19 …
Potential role of antioxidant and anti-inflammatory therapies to prevent severe SARS-Cov-2 complications
AM Fratta Pasini, C Stranieri, L Cominacini, C Mozzini - Antioxidants, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel severe acute
respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2). Here, we review the …
respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2). Here, we review the …
The good and bad of Nrf2: an update in Cancer and New perspectives in COVID-19
S Emanuele, A Celesia, A D'Anneo… - International Journal of …, 2021 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a well-known transcription factor best
recognised as one of the main regulators of the oxidative stress response. Beyond playing a …
recognised as one of the main regulators of the oxidative stress response. Beyond playing a …
Transcription factor Nrf2 as a potential therapeutic target for prevention of cytokine storm in COVID-19 patients
RA Zinovkin, OA Grebenchikov - Biochemistry (Moscow), 2020 - Springer
Nrf2 is a key transcription factor responsible for antioxidant defense in many tissues and
cells, including alveolar epithelium, endothelium, and macrophages. Furthermore, Nrf2 …
cells, including alveolar epithelium, endothelium, and macrophages. Furthermore, Nrf2 …
Dysregulation of intracellular redox homeostasis by the SARS-CoV-2 ORF6 protein
SARS-CoV-2 has evolved several strategies to overcome host cell defenses by inducing cell
injury to favour its replication. Many viruses have been reported to modulate the intracellular …
injury to favour its replication. Many viruses have been reported to modulate the intracellular …
SARS-CoV-2 inhibits NRF2-mediated antioxidant responses in airway epithelial cells and in the lung of a murine model of infection
Several viruses have been shown to modulate the transcription factor nuclear factor
erythroid 2-related factor 2 (NRF2), the master regulator of redox homeostasis. The severe …
erythroid 2-related factor 2 (NRF2), the master regulator of redox homeostasis. The severe …
[HTML][HTML] Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injury
DD Zhu, XM Tan, LQ Lu, SJ Yu, RL Jian… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 is a global pandemic and poses a major threat to human health …
syndrome coronavirus 2 is a global pandemic and poses a major threat to human health …
Role of NRF2 and Sirtuin activators in COVID-19
H Khan, S Patel, A Majumdar - Clinical Immunology, 2021 - Elsevier
COVID-19 is a pandemic requiring immediate solution for treatment because of its complex
pathophysiology. Exploration of novel targets and thus treatment will be life savers which is …
pathophysiology. Exploration of novel targets and thus treatment will be life savers which is …