Peripheral blood IL‐6 levels in systemic sclerosis patients: correlation between IL‐6 levels and clinical phenotypes
X Lin, M Ding, T Chen, S Min, D Wang… - Journal of Cosmetic …, 2022 - Wiley Online Library
Objective Detect the expression of Interleukin‐6 (IL‐6) in the serum of patients with systemic
sclerosis (SSc) and assess its association with clinical and laboratory features of the …
sclerosis (SSc) and assess its association with clinical and laboratory features of the …
Higher levels of serum interleukin-35 are associated with the severity of pulmonary fibrosis and Th2 responses in patients with systemic sclerosis
J Tang, L Lei, J Pan, C Zhao, J Wen - Rheumatology International, 2018 - Springer
The aim of the study is to investigate the levels of serum interleukin-35 (IL-35) before and
after treatment and its relationship with clinical parameters as well as the frequency of …
after treatment and its relationship with clinical parameters as well as the frequency of …
Animal models of scleroderma: current state and recent development
Y Asano, S Sato - Current rheumatology reports, 2013 - Springer
Systemic sclerosis (SSc) is a multisystem connective tissue disease characterized by three
cardinal features: immunological abnormalities, vasculopathy, and fibrosis of skin and …
cardinal features: immunological abnormalities, vasculopathy, and fibrosis of skin and …
[PDF][PDF] Role of IL-33/ST2 signaling pathway in systemic sclerosis and other fibrotic diseases
D Xu, M Barbour, HR Jiang, R Mu - Clin Exp Rheumatol, 2019 - clinexprheumatol.org
Systemic sclerosis (SSc) is a complex autoimmune disease characterised by fibrosis of the
skin and multiple internal organs. Interleukin 33 (IL-33) has recently been investigated as a …
skin and multiple internal organs. Interleukin 33 (IL-33) has recently been investigated as a …
Scleroderma peripheral B lymphocytes secrete interleukin‐6 and transforming growth factor β and activate fibroblasts
N Dumoitier, B Chaigne, A Régent… - Arthritis & …, 2017 - Wiley Online Library
Objective To study the role of B lymphocytes in systemic sclerosis (SSc). Methods Peripheral
B cell subpopulations and the production of interleukin‐6 (IL‐6) and transforming growth …
B cell subpopulations and the production of interleukin‐6 (IL‐6) and transforming growth …
Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in …
CP Denton, VH Ong, S Xu, H Chen-Harris… - Annals of the …, 2018 - ard.bmj.com
Objectives Skin fibrosis mediated by activated dermal fibroblasts is a hallmark of systemic
sclerosis (SSc), especially in the subset of patients with diffuse disease. Transforming …
sclerosis (SSc), especially in the subset of patients with diffuse disease. Transforming …
Current perspectives on the immunopathogenesis of systemic sclerosis
P Fuschiotti - ImmunoTargets and therapy, 2016 - Taylor & Francis
Systemic sclerosis (SSc or scleroderma) is a progressive and highly debilitating
autoimmune disorder characterized by inflammation, vasculopathy, and extensive fibrosis …
autoimmune disorder characterized by inflammation, vasculopathy, and extensive fibrosis …
IL-17 and related cytokines involved in systemic sclerosis: Perspectives
RSG Gonçalves, MC Pereira, AT Dantas… - …, 2018 - Taylor & Francis
Systemic sclerosis (SSc) is a multisystemic, complex, and rare disease of connective tissue,
with high morbidity and mortality, and without specific treatment. The disease is …
with high morbidity and mortality, and without specific treatment. The disease is …
Cytokine profiles in localized scleroderma and relationship to clinical features
K Kurzinski, KS Torok - Cytokine, 2011 - Elsevier
Localized scleroderma (LS) is a disfiguring autoimmune disease of the skin and underlying
tissue that mainly affects the pediatric population. Inflammation of the tissue leads to fibrosis …
tissue that mainly affects the pediatric population. Inflammation of the tissue leads to fibrosis …
Interleukin‐21 in autoimmune and inflammatory skin diseases
A Mesas‐Fernández, E Bodner, FJ Hilke… - European Journal of …, 2023 - Wiley Online Library
Studies on the role of interleukins (ILs) in autoimmune and inflammatory diseases allow for
the better understanding of pathologic mechanisms of disease and reshaping of treatment …
the better understanding of pathologic mechanisms of disease and reshaping of treatment …