Clinical and translational challenges in thyroid cancer

J Hernando, J Ros, A Arroyo… - Current Medicinal …, 2020 - ingentaconnect.com
Thyroid cancer is the most common endocrine malignancy and it accounts for 1% of all
newly diagnosed tumors. Approximately 10% of patients with differentiated thyroid …

Advances in targeted therapy and biomarker research in thyroid cancer

M Guo, Y Sun, Y Wei, J Xu, C Zhang - Frontiers in Endocrinology, 2024 - frontiersin.org
Driven by the intricacy of the illness and the need for individualized treatments, targeted
therapy and biomarker research in thyroid cancer represent an important frontier in …

Molecular targeted therapies of aggressive thyroid cancer

SM Ferrari, P Fallahi, U Politti, G Materazzi… - Frontiers in …, 2015 - frontiersin.org
Differentiated thyroid carcinomas (DTCs) that arise from follicular cells account> 90% of
thyroid cancer (TC)[papillary thyroid cancer (PTC) 90%, follicular thyroid cancer (FTC) 10%] …

Advances in the treatment of thyroid cancer in the era of molecularly targeted therapies

G Malouf, E Baudin, JC Soria, M Schlumberger - Bulletin du Cancer, 2009 - jle.com
10 Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. High prevalence of
BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the …

Perspectives on the treatment of advanced thyroid cancer: approved therapies, resistance mechanisms, and future directions

A Porter, DJ Wong - Frontiers in Oncology, 2021 - frontiersin.org
For differentiated thyroid cancer (DTC), systemic therapy with radioactive iodine (RAI) is
utilized for radiosensitive disease, while for radioiodine refractory (RAIR) disease, current …

Molecularly targeted therapies for thyroid cancers

SI Sherman - Endocrine Practice, 2009 - Elsevier
Objective To review the emerging evidence that therapies targeting key oncogenic and
signaling kinases can be effective in treatment of advanced thyroid carcinomas. Methods …

Novel inhibitor-based therapies for thyroid cancer—An update

M Ratajczak, D Gaweł, M Godlewska - International journal of molecular …, 2021 - mdpi.com
Thyroid cancers (TCs) are the most common tumors of the endocrine system and a constant
rise in the number of TC cases has been observed for the past few decades. TCs are one of …

Advances in thyroid cancer treatment: latest evidence and clinical potential

T Alonso-Gordoa, JJ Díez, M Durán… - … advances in medical …, 2015 - journals.sagepub.com
Advanced thyroid carcinoma is an infrequent tumor entity with limited treatment possibilities
until recently. The extraordinary improvement in the comprehension of genetic and …

new treatments for advanced differentiated thyroid cancers and potential mechanisms of drug resistance

S Hamidi, MC Hofmann, PC Iyer… - Frontiers in …, 2023 - frontiersin.org
The treatment of advanced, radioiodine refractory, differentiated thyroid cancers (RR-DTCs)
has undergone major advancements in the last decade, causing a paradigm shift in the …

Differentiated thyroid cancers: a comprehensive review of novel targeted therapies

KL Kojic, SL Kojic, SM Wiseman - Expert review of anticancer …, 2012 - Taylor & Francis
Differentiated thyroid carcinoma (DTC) accounts for more than 90% of new thyroid cancer
diagnoses, and includes papillary, follicular and Hürthle cell carcinoma. The prognosis for …