Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
CKDGen Consortium, KidneyGen Consortium… - Nature, 2011 - nature.com
Blood pressure is a heritable trait influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …
Genomewide linkage scan of resting blood pressure: HERITAGE Family Study
T Rice, T Rankinen, YC Chagnon, MA Province… - …, 2002 - Am Heart Assoc
The purpose of this study was to search for genomic regions influencing resting systolic
(SBP) and diastolic (DBP) blood pressure (BP) in sedentary families (baseline), and for …
(SBP) and diastolic (DBP) blood pressure (BP) in sedentary families (baseline), and for …
Genome scans for hypertension and blood pressure regulation
NJ Samani - American Journal of Hypertension, 2003 - academic.oup.com
Genome scans for hypertension and blood pressure regulation | American Journal of
Hypertension | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …
Hypertension | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …
Understanding the role of genetics in hypertension
Hypertension is a major modifiable risk factor for renal, cardiovascular, and cerebrovascular
disease, and a leading underlying cause of global mortality and morbidity. 1 Incremental …
disease, and a leading underlying cause of global mortality and morbidity. 1 Incremental …
A genome-wide association study of hypertension and blood pressure in African Americans
The evidence for the existence of genetic susceptibility variants for the common form of
hypertension (“essential hypertension”) remains weak and inconsistent. We sought genetic …
hypertension (“essential hypertension”) remains weak and inconsistent. We sought genetic …
Blood pressure loci identified with a gene-centric array
Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous
studies have identified 47 distinct genetic variants robustly associated with BP, but …
studies have identified 47 distinct genetic variants robustly associated with BP, but …
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
We carried out a trans-ancestry genome-wide association and replication study of blood
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney
Elevated blood pressure is a major risk factor for cardiovascular disease and has a
substantial genetic contribution. Genetic variation influencing blood pressure has the …
substantial genetic contribution. Genetic variation influencing blood pressure has the …
Evidence for a gene influencing blood pressure on chromosome 17: genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the …
Hypertension is a leading cause of morbidity and mortality. Efforts to identify hypertension
genes have focused on 3 approaches: mendelian disorders, candidate genes, and genome …
genes have focused on 3 approaches: mendelian disorders, candidate genes, and genome …
Lack of association of 3 functional gene variants with hypertension in African Americans
N Larson, R Hutchinson, E Boerwinkle - Hypertension, 2000 - Am Heart Assoc
African Americans are a critical population in which to study the impact of physiologically
important candidate gene mutations on the occurrence of hypertension. African Americans …
important candidate gene mutations on the occurrence of hypertension. African Americans …