The purine nucleoside adenosine is consensually identified as a major local regulator of
tissue function especially when energy supply fails to meet cellular energy demand. Due to …

Since the first description of adenosine receptors 30 years ago, based on the valuable
scientific discoveries and contributions by individuals working in the field of adenosine …

Adenosine is a physiological nucleoside which acts as an autocoid and activates G protein-
coupled membrane receptors, designated A1, A2A, A2B and A3. Adenosine plays an …

Adenosine receptors (ARs) are a four-member subfamily of G protein-coupled receptors and
are major targets of caffeine and theophylline. There are four subtypes of ARs, designated …

Adenosine is involved in a range of physiological and pathological effects through
membrane-bound receptors linked to G proteins. There are four subtypes of adenosine …

Ever since the discovery of the hypotensive and bradycardiac effects of adenosine,
adenosine receptors continue to represent promising drug targets. First, this is due to the fact …

Four types of adenosine receptors (ARs) have been identified and designated A1, A2A, A2B
and A3. During the past decades, potent antagonists have been developed for each of these …

Adenosine's diverse physiological functions are mediated by four subtypes of receptors (A1,
A2A, A2B and A3). The A1 adenosine receptor pharmacology and therapeutic application of …

Adenosine receptors are major targets of caffeine, the most commonly consumed drug in the
world. There is growing evidence that they could also be promising therapeutic targets in a …

Adenosine is a purine nucleoside, responsible for the regulation of a wide range of
physiological and pathophysiological conditions by binding with four G-protein-coupled …