Autism genetics: opportunities and challenges for clinical translation
Genetic studies have revealed the involvement of hundreds of gene variants in autism. Their
risk effects are highly variable, and they are frequently related to other conditions besides …
risk effects are highly variable, and they are frequently related to other conditions besides …
Genetic advances in autism
A Thapar, M Rutter - Journal of autism and developmental disorders, 2021 - Springer
In the last 40 years, there has been a huge increase in autism genetics research and a
rapidly growing number of discoveries. We now know autism is one of the most highly …
rapidly growing number of discoveries. We now know autism is one of the most highly …
Genetic contributions to autism spectrum disorder
A Havdahl, M Niarchou, A Starnawska… - Psychological …, 2021 - cambridge.org
Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental
conditions characterized by early childhood-onset impairments in communication and social …
conditions characterized by early childhood-onset impairments in communication and social …
Advances in autism genetics: on the threshold of a new neurobiology
BS Abrahams, DH Geschwind - Nature reviews genetics, 2008 - nature.com
Autism is a heterogeneous syndrome defined by impairments in three core domains: social
interaction, language and range of interests. Recent work has led to the identification of …
interaction, language and range of interests. Recent work has led to the identification of …
Current developments in the genetics of autism: from phenome to genome
Despite compelling evidence from twin and family studies indicating a strong genetic
involvement in the etiology of autism, the unequivocal detection of autism susceptibility …
involvement in the etiology of autism, the unequivocal detection of autism susceptibility …
Genetic risk factors for autism-spectrum disorders: A systematic review based on systematic reviews and meta-analysis
H Wei, Y Zhu, T Wang, X Zhang, K Zhang… - Journal of Neural …, 2021 - Springer
Background Based on recent evidence, more than 200 susceptibility genes have been
identified to be associated with autism until now. Correspondingly, cytogenetic abnormalities …
identified to be associated with autism until now. Correspondingly, cytogenetic abnormalities …
Genetic causes of syndromic and non‐syndromic autism
AO Caglayan - Developmental Medicine & Child Neurology, 2010 - Wiley Online Library
Aims Over the past decade, genetic tests have become available for numerous heritable
disorders, especially those whose inheritance follows the Mendelian model. Autism …
disorders, especially those whose inheritance follows the Mendelian model. Autism …
The search for autism disease genes
TH Wassink, LM Brzustowicz… - Mental retardation …, 2004 - Wiley Online Library
Autism is a heritable disorder characterized by phenotypic and genetic complexity. This
review begins by surveying current linkage, gene association, and cytogenetic studies …
review begins by surveying current linkage, gene association, and cytogenetic studies …
Genetics of autism: overview and new directions
P Szatmari, MB Jones, L Zwaigenbaum… - Journal of autism and …, 1998 - Springer
Genetic epidemiology is the study of inherited factors involved in the etiology of a disease or
disorder and uses the methods of both medical genetics and clinical epidemiology. In …
disorder and uses the methods of both medical genetics and clinical epidemiology. In …
Progress in the genetics of autism spectrum disorder
M Woodbury‐Smith, SW Scherer - Developmental Medicine & …, 2018 - Wiley Online Library
A genetic basis for autism spectrum disorder (ASD) is now well established, and with the
availability of high‐throughput microarray and sequencing platforms, major advances have …
availability of high‐throughput microarray and sequencing platforms, major advances have …