High-dimensional clustering of 4000 irritable bowel syndrome patients reveals seven distinct disease subsets
A Byale, RJ Lennon, S Byale, M Breen-Lyles… - Clinical …, 2022 - Elsevier
Background and Aims Irritable bowel syndrome (IBS) is a pain disorder classified by bowel
habits, disregarding other factors that may influence the clinical course. The aim of this study …
habits, disregarding other factors that may influence the clinical course. The aim of this study …
[HTML][HTML] Novel symptom subgroups in individuals with irritable bowel syndrome predict disease impact and burden
CJ Black, CE Ng, VC Goodoory, AC Ford - Clinical Gastroenterology and …, 2024 - Elsevier
Background & Aims Current classification systems based on bowel habit fail to capture the
multidimensional nature of irritable bowel syndrome (IBS). We previously derived and …
multidimensional nature of irritable bowel syndrome (IBS). We previously derived and …
Longitudinal follow‐up of a novel classification system for irritable bowel syndrome: natural history and prognostic value
CJ Black, Y Yiannakou, E Guthrie… - Alimentary …, 2021 - Wiley Online Library
Background Conventionally, irritable bowel syndrome (IBS) is subgrouped using
predominant stool form, yet it is a complex disorder, with multiple biopsychosocial …
predominant stool form, yet it is a complex disorder, with multiple biopsychosocial …
Mixture model analysis identifies irritable bowel syndrome subgroups characterised by specific profiles of gastrointestinal, extraintestinal somatic and psychological …
Summary Background Current subgrouping of Irritable Bowel Syndrome (IBS) is exclusively
based on stool consistency without considering other relevant gastrointestinal (GI) …
based on stool consistency without considering other relevant gastrointestinal (GI) …
Exploring new subgroups for irritable bowel syndrome using a machine learning algorithm
Irritable bowel syndrome (IBS) is a complicated gut-brain axis disorder that has typically
been classified into subgroups based on the major abnormal stool consistency and …
been classified into subgroups based on the major abnormal stool consistency and …
Subtyping irritable bowel syndrome using cluster analysis: a systematic review
D Zarei, A Saghazadeh, N Rezaei - BMC bioinformatics, 2023 - Springer
Background Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal
disorder associated with a wide range of clinical symptoms. Some researchers have used …
disorder associated with a wide range of clinical symptoms. Some researchers have used …
Factors related to irritable bowel syndrome and differences among subtypes: A cross-sectional study in the UK Biobank
K Wang, H Liu, J Liu, L Han, Z Kang, L Liang… - Frontiers in …, 2022 - frontiersin.org
Background: Irritable bowel syndrome (IBS) reduces patients' quality of life and causes great
burdens due to its unclear pathogenesis and criteria for diagnosis. This study aimed to …
burdens due to its unclear pathogenesis and criteria for diagnosis. This study aimed to …
Irritable bowel syndrome: a comparison of subtypes
NG Rey de Castro, V Miller… - Journal of …, 2015 - Wiley Online Library
Abstract Background and Aim Irritable bowel syndrome (IBS) is traditionally divided into
subtypes depending on the bowel habit abnormality, but there is little clarity in the literature …
subtypes depending on the bowel habit abnormality, but there is little clarity in the literature …
Utility of irritable bowel syndrome subtypes and most troublesome symptom in predicting disease impact and burden
M Khasawneh, FA Shaikh, CE Ng… - …, 2024 - Wiley Online Library
Background Little is known about the characteristics of individuals with irritable bowel
syndrome (IBS) according to stool subtype or the most troublesome symptom reported by the …
syndrome (IBS) according to stool subtype or the most troublesome symptom reported by the …
Cluster analysis of symptoms and health seeking behaviour differentiates subgroups of patients with severe irritable bowel syndrome
E Guthrie, F Creed, L Fernandes, J Ratcliffe… - Gut, 2003 - gut.bmj.com
Background: Irritable bowel syndrome (IBS) is a heterogeneous condition which is
diagnosed according to specific bowel symptom clusters. The aim of the present study was …
diagnosed according to specific bowel symptom clusters. The aim of the present study was …