Functional analysis of the role of glutathione peroxidase (GPx) in the ROS signaling pathway, hyphal branching and the regulation of ganoderic acid biosynthesis in …

C Li, L Shi, D Chen, A Ren, T Gao, M Zhao - Fungal Genetics and Biology, 2015 - Elsevier
Ganoderma lucidum, a hallmark of traditional Chinese medicine, has been widely used as a
pharmacologically active compound. Although numerous research studies have focused on …

Cross talk between calcium and reactive oxygen species regulates hyphal branching and ganoderic acid biosynthesis in Ganoderma lucidum under copper stress

T Gao, L Shi, T Zhang, A Ren, A Jiang… - Applied and …, 2018 - Am Soc Microbiol
Ganoderma lucidum is among the best known medicinal basidiomycetes due to its
production of many pharmacologically active compounds. To study the regulatory networks …

Effects of glutamate oxaloacetate transaminase on reactive oxygen species in Ganoderma lucidum

H Liu, J Qiao, J Shangguan, J Zhu - Applied Microbiology and …, 2023 - Springer
Nitrogen metabolism can regulate mycelial growth and secondary metabolism in
Ganoderma lucidum. As an important enzyme in intracellular amino acid metabolism …

Hydrogen‐rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum

A Ren, R Liu, ZG Miao, X Zhang, PF Cao… - Environmental …, 2017 - Wiley Online Library
Ganoderma lucidum is one of the most important medicinal fungi, but the lack of basic study
on the fungus has hindered the further development of its value. To investigate the roles of …

GCN4 regulates secondary metabolism through activation of antioxidant gene expression under nitrogen limitation conditions in Ganoderma lucidum

L Lian, L Wang, S Song, J Zhu, R Liu… - Applied and …, 2021 - Am Soc Microbiol
Nitrogen limitation has been widely reported to affect the growth and development of fungi,
and the transcription factor GCN4 (general control nonderepressible 4) is involved in …

[HTML][HTML] Heat stress-induced reactive oxygen species participate in the regulation of HSP expression, hyphal branching and ganoderic acid biosynthesis in …

R Liu, X Zhang, A Ren, DK Shi, L Shi, J Zhu… - Microbiological …, 2018 - Elsevier
Heat stress (HS) is an important environmental factor that affects the growth and metabolism
of edible fungi, but the molecular mechanism of the heat stress response (HSR) remains …

Shedding light on the mechanisms underlying the environmental regulation of secondary metabolite ganoderic acid in Ganoderma lucidum using physiological and …

A Ren, L Shi, J Zhu, H Yu, A Jiang, H Zheng… - Fungal genetics and …, 2019 - Elsevier
The secondary metabolites of fungi are often produced at very low concentrations, and until
recently the regulatory mechanisms of secondary metabolite biosynthesis have been …

The regulation of methyl jasmonate on hyphal branching and GA biosynthesis in Ganoderma lucidum partly via ROS generated by NADPH oxidase

L Shi, L Gong, X Zhang, A Ren, T Gao… - Fungal Genetics and …, 2015 - Elsevier
Ganoderma lucidum is one of the best known medicinal basidiomycetes because it
produces many pharmacologically active compounds, and methyl jasmonate (MeJA) was …

Functions of reactive oxygen species in apoptosis and ganoderic acid biosynthesis in Ganoderma lucidum

J Zhu, F Wu, S Yue, C Chen, S Song… - FEMS Microbiology …, 2019 - academic.oup.com
Ganoderma lucidum is a medicinal fungus that is widely used in traditional medicine. Fungal
PacC is recognized as an important transcription factor that functions during adaptation to …

Functions of the nicotinamide adenine dinucleotide phosphate oxidase family in Ganoderma lucidum: an essential role in ganoderic acid biosynthesis regulation …

D Mu, C Li, X Zhang, X Li, L Shi… - Environmental …, 2014 - Wiley Online Library
G anoderma lucidum has drawn worldwide interest with regard to its secondary metabolism
and pharmaceutical activity. However, the development of such research has been limited …