[HTML][HTML] CO-releasing metal carbonyl compounds as antimicrobial agents in the post-antibiotic era

LK Wareham, RK Poole, M Tinajero-Trejo - Journal of Biological Chemistry, 2015 - ASBMB
The possibility of a" post-antibiotic era" in the 21st century, in which common infections may
kill, has prompted research into radically new antimicrobials. CO-releasing molecules …

Examining the antimicrobial activity and toxicity to animal cells of different types of CO-releasing molecules

LS Nobre, H Jeremias, CC Romão, LM Saraiva - Dalton Transactions, 2016 - pubs.rsc.org
Transition metal carbonyl complexes used as CO-releasing molecules (CORMs) for
biological and therapeutic applications may exhibit interesting antimicrobial activity …

[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3

HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …

Recent advances on carbon monoxide releasing molecules for antibacterial applications

J Cheng, J Hu - ChemMedChem, 2021 - Wiley Online Library
Carbon monoxide (CO) has been known as an endogenous signaling molecule in addition
to an air pollutant. It plays a critical role in many physiological and pathological processes …

Carbon monoxide in biology and microbiology: surprising roles for the “Detroit perfume”

KS Davidge, R Motterlini, BE Mann, JL Wilson… - Advances in microbial …, 2009 - Elsevier
Carbon monoxide (CO) is a colorless, odorless gas with a reputation for being an
anthropogenic poison; there is extensive documentation of the modes of human exposure …

A role for reactive oxygen species in the antibacterial properties of carbon monoxide-releasing molecules

AFN Tavares, LS Nobre… - FEMS microbiology letters, 2012 - academic.oup.com
Carbon monoxide-releasing molecules (CO-RMs) are, in general, transition metal carbonyl
complexes that liberate controlled amounts of CO. In animal models, CO-RMs have been …

The Broad-Spectrum Antimicrobial Potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation …

LK Wareham, S McLean, R Begg, N Rana… - Antioxidants & redox …, 2018 - liebertpub.com
Abstract Aims: Carbon monoxide (CO)-releasing molecules (CORMs) are candidates for
animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a …

Antimicrobial action of carbon monoxide-releasing compounds

LS Nobre, JD Seixas, CC Romao… - Antimicrobial agents and …, 2007 - Am Soc Microbiol
Carbon monoxide (CO) is endogenously produced in the human body, mainly from the
oxidation of heme catalyzed by heme oxygenase (HO) enzymes. The induction of HO and …

CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on …

JL Wilson, LK Wareham, S McLean, R Begg… - Antioxidants & redox …, 2015 - liebertpub.com
Aims: Carbon monoxide-releasing molecules (CORMs) are being developed with the
ultimate goal of safely utilizing the therapeutic potential of CO clinically, including …

Antibacterial effects of carbon monoxide

J Louise Wilson, HE Jesse, RK Poole… - Current …, 2012 - ingentaconnect.com
Carbon monoxide (CO) is a colourless and odourless gas that has long been considered as
a potent respiratory poison. Recent advances have demonstrated its production by haem …