The physical state of human papillomavirus type 16 DNA in benign and malignant genital tumours

M Dürst, A Kleinheinz, M Hotz… - Journal of General …, 1985 - microbiologyresearch.org
Cloned DNA from human papillomavirus (HPV) type 16 was subjected to restriction enzyme
analysis. A genome size of 7.8±0.1 kb was determined and restriction maps were prepared …

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

M Boshart, L Gissmann, H Ikenberg, A Kleinheinz… - The EMBO …, 1984 - embopress.org
DNA of a new papillomavirus type was cloned from a cervical carcinoma biopsy. Two EcoRI
clones of 7.8 and 6.9 kb in length were obtained, the latter contained a 900‐bp deletion. The …

Cloning of monomeric human papillomavirus type 16 DNA integrated within cell DNA from a cervical carcinoma

T Matsukura, T Kanda, A Furuno, H Yoshikawa… - Journal of …, 1986 - Am Soc Microbiol
We have molecularly cloned and characterized monomeric human papillomavirus type 16
DNA with flanking cell DNA sequences from a cervical carcinoma. Determination of …

Analysis of integrated human papillomavirus type 16 DNA in cervical cancers: amplification of viral sequences together with cellular flanking sequences

M Wagatsuma, K Hashimoto, T Matsukura - Journal of virology, 1990 - Am Soc Microbiol
We have isolated four clones of integrated human papillomavirus type 16 (HPV-16) DNA
from four different primary cervical cancer specimens. All clones were found to be …

Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNA

L Gissmann, EM De Villiers… - International Journal of …, 1982 - Wiley Online Library
Abstract 32 P-labelled cloned HPV 6 DNA was used as probe to analyze human genital
tumors for DNA sequences homologous to HPV 6 DNA. Ninety three percent of all …

Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions

BC Das, JK Sharma… - Journal of General …, 1992 - microbiologyresearch.org
Integration of human papillomavirus (HPV) DNA into the host cell genome is believed to be
essential for malignant progression. However unambiguous detection of the physical state of …

Human papillomaviruses in Buschke-Löwenstein tumors: physical state of the DNA and identification of a tandem duplication in the noncoding region of a human …

M Boshart, H zur Hausen - Journal of Virology, 1986 - Am Soc Microbiol
Six Buschke-Löwenstein tumors, ie, highly differentiated squamous cell tumors of the genital
region, were shown to contain human papillomavirus 6 (HPV 6) or HPV 11 genomes. The …

Molecular cloning of viral DNA from human genital warts

EM de Villiers, L Gissmann, H zur Hausen - Journal of virology, 1981 - Am Soc Microbiol
The DNA of human papilloma virus type 6 (HPV 6) has been cloned in Escherichia coli K-12
by using pBR322 as vector. The DNA was cloned at the BamHI and EcoRI cleavage sites …

Cloning and characterization of the DNA of a new human papillomavirus from a woman with dysplasia of the uterine cervix

AT Lorincz, WD Lancaster, GF Temple - Journal of Virology, 1986 - Am Soc Microbiol
A previous analysis of 121 female genital tract lesions from the United States and South
America had revealed that a large number contained DNA sequences that were weakly …

Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers.

L Gissmann, L Wolnik, H Ikenberg… - Proceedings of the …, 1983 - National Acad Sciences
Human genital tumors as well as recurrent laryngeal papillomas were analyzed for the
presence of human papillomavirus (HPV) 6 and HPV 11 sequences. HPV 11 DNA was …