Rapid, sensitive and reliable ricin identification in serum samples using LC–MS/MS

L Feldberg, E Elhanany, O Laskar, O Schuster - Toxins, 2021 - mdpi.com
Ricin, a protein derived from the seeds of the castor bean plant (Ricinus communis), is a
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …

Rapid and sensitive identification of ricin in environmental samples based on lactamyl agarose beads using LC‐MS/MS (MRM)

L Feldberg, O Schuster, E Elhanany… - Journal of Mass …, 2020 - Wiley Online Library
Ricin, a plant‐derived toxin extracted from the seeds of Ricinus communis (castor bean
plant), is one of the most toxic proteins known. Ricin's high toxicity, widespread availability …

Development and validation of an ELISA kit for the detection of ricin toxins from biological specimens and environmental samples

HY Chen, H Tran, LY Foo, TW Sew… - Analytical and bioanalytical …, 2014 - Springer
Ricin is a toxin that can be easily extracted from seeds of Ricinus communis plants. Ricin is
considered to be a major bio-threat as it can be freely and easily acquired in large …

Mass spectrometric detection of ricin and its activity in food and clinical samples

SR Kalb, JR Barr - Analytical chemistry, 2009 - ACS Publications
Ricin is a potent toxin capable of inhibiting protein synthesis and causing death or
respiratory failure. Because of its high availability and lethality, ricin is considered a likely …

Detection of ricin in complex samples by immunocapture and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

E Duriez, F Fenaille, JC Tabet… - Journal of Proteome …, 2008 - ACS Publications
Ricin, the toxin component of Ricinus communis is considered as a potential chemical
weapon. Several complementary techniques are required to confirm its presence in …

Ultrasensitive detection of ricin toxin in multiple sample matrixes using single-domain antibodies

ST Gaylord, TL Dinh, ER Goldman… - Analytical …, 2015 - ACS Publications
Ricin is an extremely potent ribosomal inactivating protein listed as a Category B select
agent. Although ricin intoxication is not transmittable from person to person, even a single …

Detection of ricin intoxication in mice using serum peptide profiling by MALDI-TOF/MS

S Zhao, WS Liu, M Wang, J Li, Y Sun, N Li… - International Journal of …, 2012 - mdpi.com
Ricin toxin has been regarded as one of the most potent poisons in the plant kingdom, and
there is no effective therapeutic countermeasure or licensed vaccine against it …

[HTML][HTML] Ricin detection: tracking active toxin

WP Bozza, WH Tolleson, LAR Rosado, B Zhang - Biotechnology advances, 2015 - Elsevier
Ricin is a plant toxin with high bioterrorism potential due to its natural abundance and
potency in inducing cell death. Early detection of the active toxin is essential for developing …

Development and validation of streptavidin-biotin-based double antibody sandwich ELISA for ricin diagnosis

S Dixit, J Parashar, RK Dhaked, A Kumar… - International …, 2024 - Elsevier
Background Ricin is a potential biowarfare agent. It is a phytotoxin isolated from castor
seeds. At present there is no antidote available for ricin poisoning, patients only get …

Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation

DM Schieltz, SC McGrath, LG McWilliams… - Forensic science …, 2011 - Elsevier
In late February 2008, law enforcement officials in Las Vegas, Nevada, discovered in a hotel
room, a copy of The Anarchist Cookbook, suspected castor beans and a “white powder” …