The importance of host genetic factors in determining susceptibility to tuberculosis (TB) has
been studied extensively using various methods, such as case‐control, candidate gene and …

Genetic factors are important contributors to the development of a wide range of complex or
multifactorial diseases. For example, if one has a close relative who died of ischemic heart …

Several susceptibility-associated genetic polymorphisms have been proposed to explain
differential susceptibility to tuberculosis (TB) disease progression in different populations …

Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M. tb),
remains a leading public health problem in most parts of the world. Despite the discovery of …

Several epidemiology studies suggest that host genetic factors play important roles in
susceptibility, protection and progression of tuberculosis infection. Here we have reviewed …

Several candidate gene studies have provided evidence for a role of host genetics in
susceptibility to tuberculosis (TB). However, the results of these studies have been very …

The evidence for a human genetic component in susceptibility to tuberculosis (TB) is
incontrovertible. Quite apart from studies of rare disease events illustrating the importance of …

Only a small fraction of individuals exposed to Mycobacterium tuberculosis develop clinical
tuberculosis (TB). Over the past century, epidemiological studies have shown that human …

Materials and Methods: This is a special article compiled with reference to various case-
control studies, meta-analysis, and other research work on different genes and TB. The …

Prior to the discovery of the tubercle bacillus, the observation that tuberculosis frequently
occurred in many members of the same family convinced physicians that it was a hereditary …