▪ Abstract The high water permeability characteristic of mammalian red cell membranes is
now known to be caused by the protein AQP1. This channel freely permits movement of …

The aquaporins (AQPs) are a family of small membrane-spanning proteins (monomer size∼
30 kDa) that are expressed at plasma membranes in many cells types involved in fluid …

The aquaporin family of water channels in kidney. The longstanding puzzle of membrane
water permeability was advanced by the discovery of channel-forming integral protein …

The water permeability of biological membranes has been a longstanding problem in
physiology, but the proteins responsible for this remained unknown until discovery of the …

How water permeates cellular membranes and what this means for cell functioning and
several diseases are now emerging from the study of the aquaporins (AQPs), the water …

The aquaporins are a family of water channels expressed in several water-transporting
tissues, including the kidney. We have used a peptide-derived, affinity-purified polyclonal …

All characterized mammalian aquaporins (AQPs) are localized to plasma membranes where
they function chiefly to mediate water transport across cells. Here we show that AQP6 is …

The aquaporins (AQPs) are a family of intrinsic membrane proteins that function as water-
selective channels in the plasma membranes of the cells of many water-transporting tissues …

Although water is the major component of all biological fluids, the molecular pathways for
water transport across cell membranes eluded identification until the discovery of the …

The study of water transport began long before the molecular identification of water
channels with studies of water-permeable tissues. The discovery of the first aquaporin …