Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat
KKH Chung, PS Freestone… - Journal of …, 2011 - journals.physiology.org
Transient receptor potential melastatin 2 (TRPM2) channels are sensitive to oxidative stress,
and their activation can lead to cell death. Although these channels have been extensively …
and their activation can lead to cell death. Although these channels have been extensively …
TRPM2: a candidate therapeutic target for treating neurological diseases
JC Belrose, MF Jackson - Acta Pharmacologica Sinica, 2018 - nature.com
Transient receptor potential melastatin 2 (TRPM2) is a calcium (Ca 2+)-permeable non-
selective cation channel belonging to the TRP ion channel family. Oxidative stress-induced …
selective cation channel belonging to the TRP ion channel family. Oxidative stress-induced …
Ca2+‐dependent induction of TRPM2 currents in hippocampal neurons
ME Olah, MF Jackson, H Li, Y Perez… - The Journal of …, 2009 - Wiley Online Library
TRPM2 is a Ca2+‐permeable member of the transient receptor potential melastatin family of
cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and ADP …
cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and ADP …
Activation of steroid‐sensitive TRPM3 channels potentiates glutamatergic transmission at cerebellar Purkinje neurons from developing rats
PA Zamudio‐Bulcock, J Everett… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 119, 474–485. Abstract The functional implications of transient
receptor potential melastatin 3 (TRPM3) activation, the most recently described member of …
receptor potential melastatin 3 (TRPM3) activation, the most recently described member of …
[HTML][HTML] TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
M Nazıroğlu - Neurochemical research, 2011 - Springer
Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential 2
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …
Characterization and optimization of the novel transient receptor potential melastatin 2 antagonist tatM2NX
I Cruz-Torres, DS Backos, PS Herson - Molecular pharmacology, 2020 - ASPET
Transient receptor potential melastatin 2 (TRPM2) is a calcium-permeable channel activated
by adenosine diphosphate ribose metabolites and oxidative stress. TRPM2 contributes to …
by adenosine diphosphate ribose metabolites and oxidative stress. TRPM2 contributes to …
TRPM2 in the brain: role in health and disease
Transient receptor potential (TRP) proteins have been implicated in several cell functions as
non-selective cation channels, with about 30 different mammalian TRP channels having …
non-selective cation channels, with about 30 different mammalian TRP channels having …
Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation
TRPM2 is a member of the melastatin-related TRP (transient receptor potential) subfamily. It
is expressed in brain and lymphocytes and forms a cation channel that is activated by …
is expressed in brain and lymphocytes and forms a cation channel that is activated by …
NGF-induced reduction of an outward-rectifying TRPM7-like current in rat CA1 hippocampal neurons
SL Tian, H Jiang, Y Zeng, LL Li, J Shi - Neuroscience letters, 2007 - Elsevier
Transient receptor potential melastatin 7 (TRPM7) channels are widely expressed in the
nervous system; however, their function and regulation are largely unknown. This study …
nervous system; however, their function and regulation are largely unknown. This study …
Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans
The transient receptor potential melastatin (TRPM) protein family is an extensive group of
ion channels expressed in several types of mammalian cells. Many studies have shown that …
ion channels expressed in several types of mammalian cells. Many studies have shown that …