Gold nanoparticle interactions with endothelial cells cultured under physiological conditions
C Freese, L Anspach, RC Deller, SJ Richards… - Biomaterials …, 2017 - pubs.rsc.org
PEGylated gold nanoparticles (AuNPs) have an extended circulation time after intravenous
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …
injection in vivo and exhibit favorable properties for biosensing, diagnostic imaging, and …
[HTML][HTML] Synthesis of functionalized 10-nm polymer-coated gold particles for endothelium targeting and drug delivery
MJ Cheng, P Prabakaran, R Kumar… - Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) have been used extensively in medical research due to their
size, biocompatibility, and modifiable surface. Specific targeting and drug delivery are some …
size, biocompatibility, and modifiable surface. Specific targeting and drug delivery are some …
Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial …
T Mohamed, S Matou-Nasri, A Farooq… - International journal …, 2017 - Taylor & Francis
Background Gold nanoparticles (AuNPs) demonstrate clinical potential for drug delivery and
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
imaging diagnostics. As AuNPs aggregate in physiological fluids, polymer-surface …
Evaluation of gold nanoparticles biocompatibility: a multiparametric study on cultured endothelial cells and macrophages
A Orlando, M Colombo, D Prosperi, F Corsi… - Journal of Nanoparticle …, 2016 - Springer
Colloidal gold nanoparticles (AuNPs) have been considered an established advanced tool
in biomedicine thanks to their physicochemical properties combined with nanoscale size …
in biomedicine thanks to their physicochemical properties combined with nanoscale size …
Size-and coating-dependent uptake of polymer-coated gold nanoparticles in primary human dermal microvascular endothelial cells
A library-orientated approach is used to gain understanding of the interactions of well-
defined nanoparticles with primary human endothelial cells, which are a key component of …
defined nanoparticles with primary human endothelial cells, which are a key component of …
Uptake of poly (2-hydroxypropylmethacrylamide)-coated gold nanoparticles in microvascular endothelial cells and transport across the blood–brain barrier
The facile and modular functionalization of gold nanoparticles makes them versatile tools in
nanomedicine, for instance, photothermal therapy, contrast agents or as model …
nanomedicine, for instance, photothermal therapy, contrast agents or as model …
Uptake of gold nanoparticles in primary human endothelial cells
Gold nanoparticles (AuNPs) are relevant in nanomedicine for drug delivery in the vascular
system, where endothelial cells are the first point of contact. We investigated the uptake of …
system, where endothelial cells are the first point of contact. We investigated the uptake of …
Evaluation of gold nanoparticles toxicity towards human endothelial cells under static and flow conditions
C Fede, I Fortunati, V Weber, N Rossetto, F Bertasi… - Microvascular …, 2015 - Elsevier
A new in vitro model system, adding advection and shear stress associated with a flowing
medium, is proposed for the investigation of nanoparticles uptake and toxicity towards …
medium, is proposed for the investigation of nanoparticles uptake and toxicity towards …
Transport of gold nanoparticles by vascular endothelium from different human tissues
R Gromnicova, M Kaya, IA Romero, P Williams… - PLoS …, 2016 - journals.plos.org
The selective entry of nanoparticles into target tissues is the key factor which determines
their tissue distribution. Entry is primarily controlled by microvascular endothelial cells, which …
their tissue distribution. Entry is primarily controlled by microvascular endothelial cells, which …
Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells
Y Liu, N Rogel, K Harada, L Jarett, CH Maiorana… - …, 2017 - Taylor & Francis
In this work, we evaluated the impact of gold nanoparticles on endothelial cell behavior and
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
function beyond the influence on cell viability. Five types of gold nanoparticles were studied …
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